Frost Gamma Investments Trust bought $741K of OPK

bought $740.85k of OPK

500,000 shares @ $1.48

Increased holdings by +0.20%

22nd largest trade (out of 738)

Cluster Buy

Trade made by a 10% owner

Part of a cluster of 3 transactions by 2 insiders

Unscheduled trade

41% win rate · -6.7% median edge vs SPY (663 trades, 90-day)

Small Cap stock — insider trades carry more weight

OPKOPKO HEALTH, INC.

Health CarePharmaceuticals

1D0.00%

1W-13.48%

1M-12.86%

3M+0.83%

6M—

1Y—

Recent insider activity at OPK