Mon, May 11, 2026
May 11
184,639 shares @ $46.22
Decreased holdings by -6.50%
20th largest trade (out of 311)
Planned (10b5-1)Large Trade
“These securities were sold pursuant to a 10b5-1 plan.”Form 4 footnote
Trade made by a director
Executed under a pre-scheduled Rule 10b5-1 plan
55% win rate · +9.8% median edge vs SPY (197 trades, 90-day)
Price 32% above 200-day moving average
Win rate excludes trades classified as routine (tax, 10b5-1, exercise, gift).
Recent insider activity at SION
Jul 7Orbimed Capital Gp Viii LlcSold$3.85mJul 6Jennifer FitzpatrickSold$446.86kJun 30Orbimed Advisors LlcSold$5.27mMay 27Orbimed Advisors LlcSold$4.49kMay 8Orbimed Advisors LlcSold$2.66mMay 7Orbimed Advisors LlcSold$2.17mApr 18Orbimed Advisors LlcSold$131.24kApr 17Orbimed Capital Gp Viii LlcSold$2.34m