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Insider Trading Intelligence
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Laura Lee Sandler

ORKA
CHIEF OPERATING OFFICER · ORUKA THERAPEUTICS, INC. · CIK 0002075401
FILING MIX · LIFETIME26%/74%
BUYS
7
SELLS
20
TOTAL VALUE
$1.55M
COMPANIES
1
ACTIVE SINCE
Jul 2025
HOLDINGS NOW
241,384
AVG SELL PX
$47.83
TRADE KIND
SHOWING 27 / 27
Trades · vs SPY
Loading price series…
Performance · forward returns vs SPY
12 backtested trades · 8 horizons · 39 pending
Forward-return performance of every backtestable P/S trade by Laura Lee Sandler, measured at 8 horizons from 7 days to 2 years. Deduped per economic event so co-filings count once. Excess return = trade return minus SPY return over the same window.
HORIZONTRADESWIN RATEINSIDER RETURNSPY RETURNMEAN EXCESSMEDIAN EXCESST-STAT
7d12+50.00%+1.19%+1.21%-0.02%+0.86%—
14d12+50.00%+9.24%+0.93%+8.31%+5.75%—
30d12+50.00%+15.13%+0.15%+36.58%+35.96%—
60d12+0.00%+41.70%+3.05%+38.65%+35.61%—
90d12(6 pending)+0.00%+79.74%-0.28%+83.03%+92.58%—
180d12(9 pending)+0.00%+236.65%+9.31%+227.34%+227.34%—
1y12(12 pending)——————
2y12(12 pending)——————
How to read this: Insider Returnis the average raw return of the filer's trades over the horizon. SPY Return is what SPY did over those same windows — reference only, not a comparison. The headline alpha number is Mean Excess = Insider − SPY; green means the filer beat SPY, red means they trailed it. Win rate is the share of individual trades where the filer beat SPY. T-statvalues above 2 mean the alpha is unlikely to be chance given the sample size. "Pending" counts trades where the horizon hasn't elapsed yet; their stats are not included in the row average.
Holdings over time
ORKA · 241,384 shares · as of Jul 1, 2026
060,646121,292181,938242,5842026SHARES HELD
Trading cadence · quarterly flow
BUY ● SELL ●
2025
2025
2026
2026
2026
FLOW · 7 buys / 20 sellsCOVERAGE · 5 quarters
Form 4 filings · all activity
COMPANYTYPESHARESPRICEVALUEHELD AFTERTRADE DATEFILEDDETAILS
ORKA
ORUKA THERAPEUTICS, INC.
SALE10b5-1
10b5-1 plan
2,237$93.85$209.9K239,147Jul 1, 2026Jul 1, 2026 ↗View →
ORKA
ORUKA THERAPEUTICS, INC.
SALE10b5-1
10b5-1 plan
2,263$94.75$214.4K236,884Jul 1, 2026Jul 1, 2026 ↗View →
ORKA
ORUKA THERAPEUTICS, INC.
SALE10b5-1
10b5-1 plan
500$95.47$47.7K236,384Jul 1, 2026Jul 1, 2026 ↗View →
ORKA
ORUKA THERAPEUTICS, INC.
PURCHASE
Chief Operating Officer
5,000$7.80$39.0K241,384Jul 1, 2026Jul 1, 2026 ↗View →
ORKA
ORUKA THERAPEUTICS, INC.
SALE
Chief Operating Officer
5,000——79,996Jul 1, 2026Jul 1, 2026 ↗View →
ORKA
ORUKA THERAPEUTICS, INC.
SALE
Chief Operating Officer
600$69.69$41.8K236,384Jun 15, 2026Jun 15, 2026 ↗View →
ORKA
ORUKA THERAPEUTICS, INC.
SALE10b5-1
10b5-1 plan
300$65.10$19.5K237,684May 1, 2026May 1, 2026 ↗View →
ORKA
ORUKA THERAPEUTICS, INC.
SALE10b5-1
10b5-1 plan
200$67.16$13.4K237,084May 1, 2026May 1, 2026 ↗View →
ORKA
ORUKA THERAPEUTICS, INC.
PURCHASE
Chief Operating Officer
5,000$7.80$39.0K241,984May 1, 2026May 1, 2026 ↗View →
ORKA
ORUKA THERAPEUTICS, INC.
SALE10b5-1
10b5-1 plan
1,800$64.15$115.5K237,984May 1, 2026May 1, 2026 ↗View →
ORKA
ORUKA THERAPEUTICS, INC.
SALE10b5-1
10b5-1 plan
2,200$62.58$137.7K239,784May 1, 2026May 1, 2026 ↗View →
ORKA
ORUKA THERAPEUTICS, INC.
SALE10b5-1
10b5-1 plan
400$66.06$26.4K237,284May 1, 2026May 1, 2026 ↗View →
ORKA
ORUKA THERAPEUTICS, INC.
SALE
Chief Operating Officer
5,000——84,996May 1, 2026May 1, 2026 ↗View →
ORKA
ORUKA THERAPEUTICS, INC.
SALE10b5-1
10b5-1 plan
100$68.48$6.8K236,984May 1, 2026May 1, 2026 ↗View →
ORKA
ORUKA THERAPEUTICS, INC.
SALE
Chief Operating Officer
600$41.30$24.8K236,984Mar 16, 2026Mar 17, 2026 ↗View →
ORKA
ORUKA THERAPEUTICS, INC.
SALE
Chief Operating Officer
5,000——89,996Mar 2, 2026Mar 2, 2026 ↗View →
ORKA
ORUKA THERAPEUTICS, INC.
SALE10b5-1
10b5-1 plan
2,325$33.28$77.4K240,259Mar 2, 2026Mar 2, 2026 ↗View →
ORKA
ORUKA THERAPEUTICS, INC.
PURCHASE
Chief Operating Officer
5,000$7.80$39.0K242,584Mar 2, 2026Mar 2, 2026 ↗View →
ORKA
ORUKA THERAPEUTICS, INC.
SALE10b5-1
10b5-1 plan
2,675$33.81$90.4K237,584Mar 2, 2026Mar 2, 2026 ↗View →
ORKA
ORUKA THERAPEUTICS, INC.
PURCHASEGRANT
Stock grant
130,000——130,000Jan 23, 2026Jan 23, 2026 ↗View →
ORKA
ORUKA THERAPEUTICS, INC.
PURCHASEGRANT
Stock grant
32,500——237,584Jan 23, 2026Jan 23, 2026 ↗View →
ORKA
ORUKA THERAPEUTICS, INC.
SALE10b5-1
10b5-1 plan
1,108$29.75$33.0K205,084Jan 2, 2026Jan 2, 2026 ↗View →
ORKA
ORUKA THERAPEUTICS, INC.
SALE10b5-1
10b5-1 plan
8,748$28.17$246.4K209,336Jan 2, 2026Jan 2, 2026 ↗View →
ORKA
ORUKA THERAPEUTICS, INC.
PURCHASE
Chief Operating Officer
5,000$7.80$39.0K218,084Jan 2, 2026Jan 2, 2026 ↗View →
ORKA
ORUKA THERAPEUTICS, INC.
SALE10b5-1
10b5-1 plan
3,144$29.08$91.4K206,192Jan 2, 2026Jan 2, 2026 ↗View →
ORKA
ORUKA THERAPEUTICS, INC.
SALE
Chief Operating Officer
5,000——94,996Jan 2, 2026Jan 2, 2026 ↗View →
ORKA
ORUKA THERAPEUTICS, INC.
PURCHASEGRANT
Stock grant
25,000——25,000Jul 1, 2025Jul 1, 2025 ↗View →
Other insiders · ORKA
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About this filer
CIK 0002075401
ROLE
Chief Operating Officer
PRIMARY
ORKA
COMPANIES
1
ACTIVE SINCE
Jul 2025
MARKETPEEL · /INSIDER/0002075401DATA · SEC EDGAR · FORM 4 · CONSOLIDATED TAPE
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