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SG

Sarah Gheuens

AGIO
CHIEF MEDICAL OFFICER · AGIOS PHARMACEUTICALS, INC. · CIK 0001881190
FILING MIX · LIFETIME43%/57%
BUYS
45
SELLS
60
TOTAL VALUE
$2.58M
COMPANIES
2
ACTIVE SINCE
Dec 2021
HOLDINGS NOW
32,341
AVG SELL PX
$34.43
TRADE KIND
SHOWING 105 / 105
Trades · vs SPY
Loading price series…
Performance · forward returns vs SPY
16 backtested trades · 8 horizons · 18 pendingHow are these numbers computed? →
Forward-return performance of every backtestable P/S trade by Sarah Gheuens, measured at 8 horizons from 7 days to 2 years. Deduped per economic event so co-filings count once. Excess return = trade return minus SPY return over the same window.
HORIZONTRADESWIN RATEINSIDER RETURNSPY RETURNMEAN EXCESSMEDIAN EXCESST-STAT
7d16+56.25%-1.51%-0.68%-0.83%+0.56%—
14d16+56.25%+0.85%+0.79%+0.06%-0.45%—
30d16+62.50%-5.28%+1.83%-7.10%-10.57%—
60d16+62.50%-3.52%+2.40%-5.06%-6.50%—
90d16+43.75%+1.27%+4.89%-3.63%-3.21%—
180d16(1 pending)+60.00%+2.65%+10.19%-7.54%-32.34%—
1y16(6 pending)+40.00%+14.78%+20.84%-6.06%-13.05%—
2y16(11 pending)+20.00%+12.62%+42.12%-29.50%-30.48%—
How to read this: Insider Returnis the average raw return of the filer's trades over the horizon. SPY Return is what SPY did over those same windows — reference only, not a comparison. The headline alpha number is Mean Excess = Insider − SPY; green means the filer beat SPY, red means they trailed it. Win rate is the share of individual trades where the filer beat SPY. T-statvalues above 2 mean the alpha is unlikely to be chance given the sample size. "Pending" counts trades where the horizon hasn't elapsed yet; their stats are not included in the row average.
Holdings over time
AGIO · 0 shares · as of Jul 1, 2026
022,16344,32666,48988,65220222023202420252026SHARES HELD
Trading cadence · quarterly flow
BUY ● SELL ●
2021
2022
2022
2022
2022
2023
2023
2023
2023
2024
2024
2024
2024
2025
2025
2025
2025
2026
2026
2026
FLOW · 45 buys / 60 sellsCOVERAGE · 20 quarters
Form 4 filings · all activity
COMPANYTYPESHARESPRICEVALUEHELD AFTERTRADE DATEFILEDDETAILS
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE
Chief Medical Officer
8,375——0Jul 1, 2026Jul 2, 2026 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE10b5-1
10b5-1 plan
4,007$37.56$150.5K84,645Jul 1, 2026Jul 2, 2026 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
PURCHASE
Chief Medical Officer
8,375——88,652Jul 1, 2026Jul 2, 2026 ↗View →
VRDN
VIRIDIAN THERAPEUTICS, INC.DE
PURCHASEGRANT
Stock grant
32,341——32,341Jul 1, 2026Jul 2, 2026 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
PURCHASEGRANT
Stock grant
3,000——3,000Jun 18, 2026Jun 23, 2026 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE
Chief Medical Officer
3,000——9,000Jun 18, 2026Jun 23, 2026 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
PURCHASE
Chief Medical Officer
8,500——83,217Apr 2, 2026Apr 6, 2026 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE
Chief Medical Officer
8,500——8,500Apr 2, 2026Apr 6, 2026 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE10b5-1
10b5-1 plan
2,940$34.71$102.0K80,277Apr 2, 2026Apr 6, 2026 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE
Chief Medical Officer
5,666——5,667Mar 2, 2026Mar 3, 2026 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE10b5-1
10b5-1 plan
1,681$28.96$48.7K71,593Mar 2, 2026Mar 3, 2026 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE
Chief Medical Officer
4,000——0Mar 2, 2026Mar 3, 2026 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
PURCHASE
Chief Medical Officer
5,666——73,274Mar 2, 2026Mar 3, 2026 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE
Chief Medical Officer
4,000——8,000Mar 2, 2026Mar 3, 2026 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE10b5-1
10b5-1 plan
1,187$28.96$34.4K74,406Mar 2, 2026Mar 3, 2026 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
PURCHASE
Chief Medical Officer
4,000——68,795Mar 2, 2026Mar 3, 2026 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
PURCHASE
Chief Medical Officer
4,000——75,593Mar 2, 2026Mar 3, 2026 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE10b5-1
10b5-1 plan
1,187$28.96$34.4K67,608Mar 2, 2026Mar 3, 2026 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
PURCHASEGRANT
Stock grant
22,000——22,000Mar 1, 2026Mar 3, 2026 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
PURCHASEGRANT
Stock grant
52,000——52,000Mar 1, 2026Mar 3, 2026 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
PURCHASEGRANT
Stock grant
14,000——14,000Mar 1, 2026Mar 3, 2026 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
PURCHASE
Chief Medical Officer
6,000——67,727Dec 30, 2025Jan 2, 2026 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE10b5-1
10b5-1 plan
2,932$27.09$79.4K64,795Dec 30, 2025Jan 2, 2026 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE
Chief Medical Officer
6,000——0Dec 30, 2025Jan 2, 2026 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE10b5-1
10b5-1 plan
2,454$43.78$107.4K61,727Nov 11, 2025Nov 13, 2025 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE
Chief Medical Officer
2,454——26,130Nov 11, 2025Nov 13, 2025 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
PURCHASE
Chief Medical Officer
2,454$25.01$61.4K64,181Nov 11, 2025Nov 13, 2025 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE10b5-1
10b5-1 plan
200$43.81$8.8K61,727Oct 30, 2025Nov 3, 2025 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE
Chief Medical Officer
200——28,584Oct 30, 2025Nov 3, 2025 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
PURCHASE
Chief Medical Officer
200$25.01$5.0K61,927Oct 30, 2025Nov 3, 2025 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE
Chief Medical Officer
3,302——28,784Oct 27, 2025Oct 29, 2025 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
PURCHASE
Chief Medical Officer
3,302$25.01$82.6K65,029Oct 27, 2025Oct 29, 2025 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE10b5-1
10b5-1 plan
3,302$43.92$145.0K61,727Oct 27, 2025Oct 29, 2025 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE
Chief Medical Officer
11,914——32,086Jul 9, 2025Jul 11, 2025 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE10b5-1
10b5-1 plan
11,067$37.93$419.8K62,118Jul 9, 2025Jul 11, 2025 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE10b5-1
10b5-1 plan
847$38.76$32.8K61,271Jul 9, 2025Jul 11, 2025 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
PURCHASE
Chief Medical Officer
11,914$25.01$298.0K73,185Jul 9, 2025Jul 11, 2025 ↗View →
VRDN
VIRIDIAN THERAPEUTICS, INC.DE
PURCHASEGRANT
Stock grant
21,000——21,000Jul 1, 2025Jul 2, 2025 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE
Chief Medical Officer
8,374——8,375Jul 1, 2025Jul 3, 2025 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE10b5-1
10b5-1 plan
4,091$34.17$139.8K61,271Jul 1, 2025Jul 3, 2025 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
PURCHASE
Chief Medical Officer
8,374——65,362Jul 1, 2025Jul 3, 2025 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE10b5-1
10b5-1 plan
2,909$33.54$97.6K56,988Jun 24, 2025Jun 26, 2025 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
PURCHASE
Chief Medical Officer
6,000——59,897Jun 24, 2025Jun 26, 2025 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE
Chief Medical Officer
6,000——6,000Jun 24, 2025Jun 26, 2025 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE10b5-1
10b5-1 plan
1,681$35.54$59.7K53,897Mar 3, 2025Mar 4, 2025 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE10b5-1
10b5-1 plan
1,137$35.54$40.4K47,098Mar 3, 2025Mar 4, 2025 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE10b5-1
10b5-1 plan
1,187$35.54$42.2K49,911Mar 3, 2025Mar 4, 2025 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
PURCHASE
Chief Medical Officer
3,833——48,235Mar 1, 2025Mar 4, 2025 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
PURCHASEGRANT
Stock grant
12,000——12,000Mar 1, 2025Mar 4, 2025 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
PURCHASEGRANT
Stock grant
43,500——43,500Mar 1, 2025Mar 4, 2025 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE
Chief Medical Officer
5,667——11,333Mar 1, 2025Mar 4, 2025 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
PURCHASE
Chief Medical Officer
4,000——51,098Mar 1, 2025Mar 4, 2025 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE
Chief Medical Officer
4,000——4,000Mar 1, 2025Mar 4, 2025 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
PURCHASE
Chief Medical Officer
5,667——55,578Mar 1, 2025Mar 4, 2025 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE
Chief Medical Officer
3,833——0Mar 1, 2025Mar 4, 2025 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE
Chief Medical Officer
8,375——16,749Jul 1, 2024Jul 3, 2024 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE10b5-1
10b5-1 plan
3,705$43.85$162.5K43,736Jul 1, 2024Jul 3, 2024 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
PURCHASE
Chief Medical Officer
8,375——47,441Jul 1, 2024Jul 3, 2024 ↗View →
VRDN
VIRIDIAN THERAPEUTICS, INC.DE
PURCHASEGRANT
Stock grant
21,000——21,000Jun 26, 2024Jun 28, 2024 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE10b5-1
10b5-1 plan
1,349$32.57$43.9K39,066Mar 5, 2024Mar 5, 2024 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE10b5-1
10b5-1 plan
1,293$32.57$42.1K36,415Mar 5, 2024Mar 5, 2024 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE
Chief Medical Officer
4,000——8,000Mar 1, 2024Mar 5, 2024 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
PURCHASE
Chief Medical Officer
4,000——40,415Mar 1, 2024Mar 5, 2024 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
PURCHASEGRANT
Stock grant
17,000——17,000Mar 1, 2024Mar 5, 2024 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
PURCHASEGRANT
Stock grant
60,000——60,000Mar 1, 2024Mar 5, 2024 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
PURCHASE
Chief Medical Officer
3,834——37,708Mar 1, 2024Mar 5, 2024 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE
Chief Medical Officer
3,834——3,833Mar 1, 2024Mar 5, 2024 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE10b5-1
10b5-1 plan
642$25.14$16.1K33,431Feb 14, 2024Feb 14, 2024 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
PURCHASE
Chief Medical Officer
2,162——34,073Feb 12, 2024Feb 14, 2024 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE
Chief Medical Officer
2,162——0Feb 12, 2024Feb 14, 2024 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE10b5-1
10b5-1 plan
1,708$21.64$37.0K31,911Jan 24, 2024Jan 24, 2024 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE
Chief Medical Officer
5,750——0Jan 20, 2024Jan 24, 2024 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
PURCHASE
Chief Medical Officer
5,750——33,619Jan 20, 2024Jan 24, 2024 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE10b5-1
10b5-1 plan
1,789$22.99$41.1K27,869Jan 9, 2024Jan 9, 2024 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
PURCHASE
Chief Medical Officer
5,000——29,658Jan 5, 2024Jan 9, 2024 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE
Chief Medical Officer
5,000——0Jan 5, 2024Jan 9, 2024 ↗View →
VRDN
VIRIDIAN THERAPEUTICS, INC.DE
PURCHASEGRANT
Stock grant
40,000——40,000Sep 21, 2023Sep 25, 2023 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE10b5-1
10b5-1 plan
1,707$28.36$48.4K24,159Jun 30, 2023Jun 30, 2023 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
PURCHASE
Chief Medical Officer
5,750——25,866Jun 28, 2023Jun 30, 2023 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE
Chief Medical Officer
5,750——5,750Jun 28, 2023Jun 30, 2023 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE
Chief Medical Officer
1,134$25.02$28.4K20,116Mar 3, 2023Mar 3, 2023 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
PURCHASE
Chief Medical Officer
3,833——21,250Mar 1, 2023Mar 3, 2023 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
PURCHASEGRANT
Stock grant
12,000——12,000Mar 1, 2023Mar 3, 2023 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
PURCHASEGRANT
Stock grant
44,000——44,000Mar 1, 2023Mar 3, 2023 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE
Chief Medical Officer
3,833——7,667Mar 1, 2023Mar 3, 2023 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE
Chief Medical Officer
758$28.44$21.6K17,009Feb 14, 2023Feb 14, 2023 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE
Chief Medical Officer
2,162——2,162Feb 10, 2023Feb 14, 2023 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
PURCHASE
Chief Medical Officer
2,162——17,767Feb 10, 2023Feb 14, 2023 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE
Chief Medical Officer
2,783$28.48$79.3K15,605Dec 28, 2022Dec 28, 2022 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE
Chief Medical Officer
9,375——0Dec 23, 2022Dec 28, 2022 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
PURCHASE
Chief Medical Officer
9,375——18,388Dec 23, 2022Dec 28, 2022 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE
Chief Medical Officer
248$28.83$7.1K9,013Dec 6, 2022Dec 6, 2022 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE
Chief Medical Officer
833——0Dec 2, 2022Dec 6, 2022 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
PURCHASE
Chief Medical Officer
833——9,261Dec 2, 2022Dec 6, 2022 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
PURCHASEGRANT
Stock grant
11,500——11,500Mar 1, 2022Mar 3, 2022 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
PURCHASEGRANT
Stock grant
41,000——41,000Mar 1, 2022Mar 3, 2022 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE
Chief Medical Officer
955$29.08$27.8K7,768Feb 22, 2022Feb 23, 2022 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE
Chief Medical Officer
3,271——3,272Feb 18, 2022Feb 23, 2022 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
PURCHASE
Chief Medical Officer
3,271——8,723Feb 18, 2022Feb 23, 2022 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE
Chief Medical Officer
2,162——4,324Feb 10, 2022Feb 14, 2022 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE
Chief Medical Officer
758$31.43$23.8K5,452Feb 10, 2022Feb 14, 2022 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
PURCHASE
Chief Medical Officer
2,162——6,210Feb 10, 2022Feb 14, 2022 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
PURCHASE
Chief Medical Officer
834——4,296Dec 2, 2021Dec 7, 2021 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE
Chief Medical Officer
834——833Dec 2, 2021Dec 7, 2021 ↗View →
AGIO
AGIOS PHARMACEUTICALS, INC.
SALE
Chief Medical Officer
248$35.00$8.7K4,048Dec 2, 2021Dec 7, 2021 ↗View →
Other insiders · AGIO
Loading peer insiders…
About this filer
CIK 0001881190
ROLE
Chief Medical Officer
PRIMARY
AGIO
COMPANIES
2
ACTIVE SINCE
Dec 2021
MARKETPEEL · /INSIDER/0001881190DATA · SEC EDGAR · FORM 4 · CONSOLIDATED TAPE
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