Redmile Biopharma Investments Iii, L.p.

TRDA

10% OWNER · ENTRADA THERAPEUTICS, INC. · CIK 0001838746

FILING MIX · LIFETIME67%/33%

BUYS

SELLS

TOTAL VALUE

$20.00M

COMPANIES

ACTIVE SINCE

Nov 2021

HOLDINGS NOW

1,954,420

AVG SELL PX

—

Trades · vs SPY

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Performance · forward returns vs SPY

1 backtested trades · 8 horizonsHow are these numbers computed? →

Forward-return performance of every backtestable P/S trade by Redmile Biopharma Investments Iii, L.p., measured at 8 horizons from 7 days to 2 years. Deduped per economic event so co-filings count once. Excess return = trade return minus SPY return over the same window.

HORIZON	TRADES	WIN RATE	INSIDER RETURN	SPY RETURN	MEAN EXCESS	MEDIAN EXCESS	T-STAT
7d	1	+100.00%	+14.05%	+1.19%	+12.87%	+12.87%	—
14d	1	+100.00%	+34.22%	+1.60%	+32.63%	+32.63%	—
30d	1	+100.00%	+13.70%	-0.98%	+14.67%	+14.67%	—
60d	1	+0.00%	-32.81%	+3.19%	-36.00%	-36.00%	—
90d	1	+0.00%	-56.55%	-2.25%	-54.30%	-54.30%	—
180d	1	+0.00%	-74.65%	-9.67%	-64.98%	-64.98%	—
1y	1	+0.00%	-14.09%	-17.61%	+3.52%	+3.52%	—
2y	1	+0.00%	-38.50%	-3.84%	-34.66%	-34.66%	—

How to read this: Insider Returnis the average raw return of the filer's trades over the horizon. SPY Return is what SPY did over those same windows — reference only, not a comparison. The headline alpha number is Mean Excess = Insider − SPY; green means the filer beat SPY, red means they trailed it. Win rate is the share of individual trades where the filer beat SPY. T-statvalues above 2 mean the alpha is unlikely to be chance given the sample size. "Pending" counts trades where the horizon hasn't elapsed yet; their stats are not included in the row average.

Holdings over time

TRDA · 1,954,420 shares · as of Nov 2, 2021

Trading cadence · quarterly flow

BUY ● SELL ●

2021

FLOW · 2 buys / 1 sellsCOVERAGE · 1 quarters

Form 4 filings · all activity

COMPANY	TYPE	SHARES	PRICE	VALUE	HELD AFTER	TRADE DATE	FILED	DETAILS
TRDA ENTRADA THERAPEUTICS, INC.	SALE	954,420	—	—	0	Nov 2, 2021	Nov 4, 2021 ↗	View →
TRDA ENTRADA THERAPEUTICS, INC.	PURCHASE	954,420	—	—	954,420	Nov 2, 2021	Nov 4, 2021 ↗	View →
TRDA ENTRADA THERAPEUTICS, INC.	PURCHASE	1,000,000	$20.00	$20.00M	1,954,420	Nov 2, 2021	Nov 4, 2021 ↗	View →

Other insiders · TRDA

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About this filer

CIK 0001838746

ROLE

10% Owner

PRIMARY

TRDA

COMPANIES

ACTIVE SINCE

Nov 2021

MARKETPEEL · /INSIDER/0001838746DATA · SEC EDGAR · FORM 4 · CONSOLIDATED TAPE

Redmile Biopharma Investments Iii, L.p.

The morning brief, before the bell.