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Pricing
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JH

James C. Hamilton

ARWR
CHIEF MEDICAL OFFICER · ARROWHEAD PHARMACEUTICALS, INC. · CIK 0001830755
FILING MIX · LIFETIME10%/90%
BUYS
6
SELLS
56
TOTAL VALUE
$14.39M
COMPANIES
1
ACTIVE SINCE
Jan 2021
HOLDINGS NOW
226,958
AVG SELL PX
$46.91
TRADE KIND
SHOWING 62 / 62
Trades · vs SPY
Loading price series…
Performance · forward returns vs SPY
56 backtested trades · 8 horizons · 33 pending
Forward-return performance of every backtestable P/S trade by James C. Hamilton, measured at 8 horizons from 7 days to 2 years. Deduped per economic event so co-filings count once. Excess return = trade return minus SPY return over the same window.
HORIZONTRADESWIN RATEINSIDER RETURNSPY RETURNMEAN EXCESSMEDIAN EXCESST-STAT
7d56+53.57%-0.43%+1.04%-1.47%-1.68%-1.14
14d56+55.36%-1.56%+0.53%-2.09%-6.51%-1.86
30d56+57.14%+0.55%+2.38%-1.86%-6.47%-0.90
60d56+82.14%-6.45%+1.41%-7.86%-15.37%-2.45
90d56(1 pending)+89.09%-8.15%+3.47%-12.10%-19.81%-2.18
180d56(2 pending)+77.78%+0.46%+7.58%-7.13%-25.57%-0.97
1y56(14 pending)+95.24%-16.09%+14.66%-30.75%-41.95%-3.06
2y56(16 pending)+75.00%-12.43%+29.25%-41.67%-51.00%-4.52
How to read this: Insider Returnis the average raw return of the filer's trades over the horizon. SPY Return is what SPY did over those same windows — reference only, not a comparison. The headline alpha number is Mean Excess = Insider − SPY; green means the filer beat SPY, red means they trailed it. Win rate is the share of individual trades where the filer beat SPY. T-statvalues above 2 mean the alpha is unlikely to be chance given the sample size. "Pending" counts trades where the horizon hasn't elapsed yet; their stats are not included in the row average.
Holdings over time
ARWR · 226,958 shares · as of Apr 23, 2026
076,213152,426228,638304,851202120222023202420252026SHARES HELD
Trading cadence · quarterly flow
BUY ● SELL ●
2021
2021
2021
2021
2022
2022
2022
2022
2023
2023
2023
2023
2024
2024
2024
2024
2025
2025
2025
2025
2026
2026
FLOW · 6 buys / 56 sellsCOVERAGE · 22 quarters
Form 4 filings · all activity
COMPANYTYPESHARESPRICEVALUEHELD AFTERTRADE DATEFILEDDETAILS
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
SALE10b5-1
10b5-1 plan
10,000$75.00$750.0K226,958Apr 23, 2026Apr 24, 2026 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
SALE10b5-1
10b5-1 plan
10,000$64.19$641.9K236,958Mar 5, 2026Mar 9, 2026 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
PURCHASEGRANT
Stock grant
75,000——246,958Jan 6, 2026Jan 8, 2026 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
SALE10b5-1
10b5-1 plan
1,200$64.49$77.4K172,704Jan 5, 2026Jan 5, 2026 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
SALE10b5-1
10b5-1 plan
12,711$63.95$812.9K173,904Jan 5, 2026Jan 5, 2026 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
SALE10b5-1
10b5-1 plan
4,625$61.24$283.2K207,497Jan 5, 2026Jan 5, 2026 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
SALE10b5-1
10b5-1 plan
6,090$62.28$379.3K201,407Jan 5, 2026Jan 5, 2026 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
SALE10b5-1
10b5-1 plan
14,792$63.01$932.0K186,615Jan 5, 2026Jan 5, 2026 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
SALE10b5-1
10b5-1 plan
309$68.00$21.0K171,958Jan 5, 2026Jan 5, 2026 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
SALE10b5-1
10b5-1 plan
437$65.97$28.8K172,267Jan 5, 2026Jan 5, 2026 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
SALE10b5-1
10b5-1 plan
20,000$35.00$700.0K212,122Oct 1, 2025Oct 3, 2025 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
SALE10b5-1
10b5-1 plan
15,000$30.00$450.0K232,122Sep 12, 2025Sep 16, 2025 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
SALE10b5-1
10b5-1 plan
15,000$25.00$375.0K247,122Sep 2, 2025Sep 4, 2025 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
SALE10b5-1
10b5-1 plan
9,389$20.00$187.8K262,122Aug 15, 2025Aug 15, 2025 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
SALE10b5-1
10b5-1 plan
611$20.00$12.2K271,511Aug 13, 2025Aug 15, 2025 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
SALE10b5-1
10b5-1 plan
21,758$19.68$428.2K283,093Jan 6, 2025Jan 7, 2025 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
SALE10b5-1
10b5-1 plan
10,971$20.11$220.6K272,122Jan 6, 2025Jan 7, 2025 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
PURCHASEGRANT
Stock grant
100,000——304,851Jan 4, 2025Jan 7, 2025 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
SALE
Chief Discovery/Trans Medicine
6,000$28.03$168.2K204,851Apr 1, 2024Apr 3, 2024 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
SALE10b5-1
10b5-1 plan
3,702$37.37$138.3K210,851Jan 12, 2024Jan 17, 2024 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
SALE10b5-1
10b5-1 plan
4,238$36.47$154.6K214,553Jan 12, 2024Jan 17, 2024 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
SALE10b5-1
10b5-1 plan
1,800$34.00$61.2K249,134Jan 5, 2024Jan 5, 2024 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
SALE10b5-1
10b5-1 plan
12,343$35.65$440.0K228,791Jan 5, 2024Jan 5, 2024 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
SALE10b5-1
10b5-1 plan
8,000$34.94$279.5K241,134Jan 5, 2024Jan 5, 2024 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
SALE10b5-1
10b5-1 plan
10,000$35.00$350.0K218,791Jan 5, 2024Jan 5, 2024 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
PURCHASEGRANT
Stock grant
75,000——250,934Jan 4, 2024Jan 5, 2024 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
SALE10b5-1
10b5-1 plan
2,300$32.52$74.8K176,434Jan 3, 2024Jan 5, 2024 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
SALE10b5-1
10b5-1 plan
3,500$31.81$111.3K178,734Jan 3, 2024Jan 5, 2024 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
SALE10b5-1
10b5-1 plan
500$33.30$16.6K175,934Jan 3, 2024Jan 5, 2024 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
SALE
3,000$35.53$106.6K188,484Jun 30, 2023Jun 30, 2023 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
SALE
7,230$37.40$270.4K198,057Jan 5, 2023Jan 6, 2023 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
SALE
6,573$37.40$245.8K191,484Jan 5, 2023Jan 6, 2023 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
PURCHASEGRANT
Stock grant
60,000——205,287Jan 4, 2023Jan 5, 2023 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
SALE
300$39.56$11.9K145,534Jan 3, 2023Jan 5, 2023 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
SALE
136$40.54$5.5K151,158Jan 3, 2023Jan 5, 2023 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
SALE
1,194$37.46$44.7K154,431Jan 3, 2023Jan 5, 2023 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
SALE
1,642$37.49$61.6K149,516Jan 3, 2023Jan 5, 2023 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
SALE
3,682$38.52$141.8K145,834Jan 3, 2023Jan 5, 2023 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
SALE
247$40.52$10.0K145,287Jan 3, 2023Jan 5, 2023 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
SALE
300$39.74$11.9K151,294Jan 3, 2023Jan 5, 2023 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
SALE
2,837$38.53$109.3K151,594Jan 3, 2023Jan 5, 2023 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
SALE
1,100$62.64$68.9K156,385Jan 5, 2022Jan 6, 2022 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
SALE
700$63.68$44.6K155,685Jan 5, 2022Jan 6, 2022 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
SALE
2,100$61.84$129.9K157,485Jan 5, 2022Jan 6, 2022 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
SALE
60$64.35$3.9K155,625Jan 5, 2022Jan 6, 2022 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
SALE
2,290$60.51$138.6K159,585Jan 5, 2022Jan 6, 2022 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
SALE
802$67.39$54.0K163,024Jan 4, 2022Jan 6, 2022 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
SALE
649$68.12$44.2K162,375Jan 4, 2022Jan 6, 2022 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
SALE
9,955$64.89$646.0K171,295Jan 4, 2022Jan 6, 2022 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
SALE
7,469$65.59$489.9K163,826Jan 4, 2022Jan 6, 2022 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
SALE
500$69.38$34.7K161,875Jan 4, 2022Jan 6, 2022 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
PURCHASEGRANT
Stock grant
55,000——181,250Jan 1, 2022Jan 4, 2022 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
SALE
6,186$80.97$500.9K130,064Jan 14, 2021Jan 15, 2021 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
SALE
3,814$81.82$312.1K126,250Jan 14, 2021Jan 15, 2021 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
SALE
14,708$72.67$1.07M136,250Jan 6, 2021Jan 7, 2021 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
SALE
3,967$72.05$285.8K150,958Jan 6, 2021Jan 7, 2021 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
SALE
700$70.89$49.6K154,925Jan 6, 2021Jan 7, 2021 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
SALE
3,300$72.19$238.2K167,900Jan 5, 2021Jan 7, 2021 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
SALE
10,350$72.91$754.6K157,550Jan 5, 2021Jan 7, 2021 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
SALE
3,800$71.09$270.1K171,200Jan 5, 2021Jan 7, 2021 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
SALE
1,925$73.93$142.3K155,625Jan 5, 2021Jan 7, 2021 ↗View →
ARWR
ARROWHEAD PHARMACEUTICALS, INC.
PURCHASEGRANT
Stock grant
50,000——175,000Jan 1, 2021Jan 5, 2021 ↗View →
Other insiders · ARWR
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About this filer
CIK 0001830755
ROLE
Chief Medical Officer
PRIMARY
ARWR
COMPANIES
1
ACTIVE SINCE
Jan 2021
MARKETPEEL · /INSIDER/0001830755DATA · SEC EDGAR · FORM 4 · CONSOLIDATED TAPE
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