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Insider Trading Intelligence
Pricing
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RP

Richard A. Paulson

KPTI
PRESIDENT AND CEO · KARYOPHARM THERAPEUTICS INC. · CIK 0001804460
FILING MIX · LIFETIME25%/75%
BUYS
15
SELLS
45
TOTAL VALUE
$869.8K
COMPANIES
1
ACTIVE SINCE
Mar 2020
HOLDINGS NOW
269,747
AVG SELL PX
$2.87
TRADE KIND
SHOWING 60 / 60
Trades · vs SPY
Loading price series…
Performance · forward returns vs SPY
44 backtested trades · 8 horizons · 15 pendingHow are these numbers computed? →
Forward-return performance of every backtestable P/S trade by Richard A. Paulson, measured at 8 horizons from 7 days to 2 years. Deduped per economic event so co-filings count once. Excess return = trade return minus SPY return over the same window.
HORIZONTRADESWIN RATEINSIDER RETURNSPY RETURNMEAN EXCESSMEDIAN EXCESST-STAT
7d44+56.82%-2.14%-0.03%-2.11%-2.83%-1.06
14d44+68.18%-5.11%-0.02%-5.09%-6.52%-2.56
30d44+61.36%-3.64%+0.46%-4.10%-7.28%-1.23
60d44+79.55%-11.53%+1.86%-13.39%-14.26%-4.03
90d44+75.00%-17.10%+3.62%-21.00%-27.15%-5.40
180d44(1 pending)+81.40%-28.34%+8.56%-36.90%-41.68%-9.02
1y44(2 pending)+92.86%-48.59%+18.91%-67.50%-72.93%-14.71
2y44(12 pending)+100.00%-70.52%+43.73%-115.58%-118.03%-31.47
How to read this: Insider Returnis the average raw return of the filer's trades over the horizon. SPY Return is what SPY did over those same windows — reference only, not a comparison. The headline alpha number is Mean Excess = Insider − SPY; green means the filer beat SPY, red means they trailed it. Win rate is the share of individual trades where the filer beat SPY. T-statvalues above 2 mean the alpha is unlikely to be chance given the sample size. "Pending" counts trades where the horizon hasn't elapsed yet; their stats are not included in the row average.
Holdings over time
KPTI · 269,747 shares · as of May 14, 2026
0316,063632,127948,1901,264,253202120222023202420252026SHARES HELD
Trading cadence · quarterly flow
BUY ● SELL ●
2020
2020
2020
2020
2021
2021
2021
2021
2022
2022
2022
2022
2023
2023
2023
2023
2024
2024
2024
2024
2025
2025
2025
2025
2026
2026
FLOW · 15 buys / 45 sellsCOVERAGE · 26 quarters
Form 4 filings · all activity
COMPANYTYPESHARESPRICEVALUEHELD AFTERTRADE DATEFILEDDETAILS
KPTI
KARYOPHARM THERAPEUTICS INC.
SALE
President and CEO
2,203$9.50$20.9K269,747May 14, 2026May 15, 2026 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
PURCHASEGRANT
Stock grant
4,920——271,950May 13, 2026May 15, 2026 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
SALE
President and CEO
12,361$9.41$116.3K267,030Mar 2, 2026Mar 3, 2026 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
PURCHASEGRANT
Stock grant
81,060——279,391Feb 5, 2026Feb 9, 2026 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
PURCHASEGRANT
Stock grant
114,285——198,331Oct 15, 2025Oct 16, 2025 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
SALE
President and CEO
1,257$6.43$8.1K84,046Sep 15, 2025Sep 16, 2025 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
PURCHASEGRANT
Stock grant
2,800——85,303Sep 12, 2025Sep 16, 2025 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
SALE
President and CEO
236$7.12$1.7K82,503May 6, 2025May 7, 2025 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
SALE
President and CEO
245$3.74$91682,739Apr 4, 2025Apr 7, 2025 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
SALE
President and CEO
11,694$6.29$73.6K82,984Mar 4, 2025Mar 6, 2025 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
PURCHASEGRANT
Stock grant
20,000——94,678Feb 28, 2025Mar 4, 2025 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
PURCHASEGRANT
Stock grant
40,000——40,000Feb 28, 2025Mar 4, 2025 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
SALE
President and CEO
4,099$0.65$2.7K1,120,158Feb 4, 2025Feb 5, 2025 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
SALE
President and CEO
4,055$0.78$3.2K1,124,257Jan 6, 2025Jan 7, 2025 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
SALE
President and CEO
3,620$0.81$2.9K1,128,312Dec 4, 2024Dec 5, 2024 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
SALE
President and CEO
3,675$0.91$3.3K1,131,932Nov 5, 2024Nov 6, 2024 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
SALE
President and CEO
3,607$0.88$3.2K1,135,607Oct 4, 2024Oct 7, 2024 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
SALE
President and CEO
3,667$0.72$2.6K1,139,214Sep 4, 2024Sep 5, 2024 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
SALE
President and CEO
3,608$0.93$3.4K1,142,881Aug 6, 2024Aug 8, 2024 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
SALE
President and CEO
3,616$0.85$3.1K1,146,489Jul 5, 2024Jul 9, 2024 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
SALE
President and CEO
3,592$0.99$3.6K1,150,105Jun 4, 2024Jun 6, 2024 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
SALE
President and CEO
3,576$1.13$4.0K1,153,697May 6, 2024May 7, 2024 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
SALE
President and CEO
3,563$1.29$4.6K1,157,273Apr 4, 2024Apr 5, 2024 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
SALE
President and CEO
3,573$1.30$4.6K1,160,836Mar 5, 2024Mar 6, 2024 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
SALE
President and CEO
19,374$1.20$23.2K1,164,409Mar 1, 2024Mar 4, 2024 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
SALE
President and CEO
80,470$1.17$94.1K1,183,783Feb 29, 2024Mar 4, 2024 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
PURCHASEGRANT
Stock grant
442,800——1,264,253Feb 28, 2024Feb 29, 2024 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
SALE
President and CEO
4,012$1.59$6.4K821,453Feb 6, 2024Feb 8, 2024 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
PURCHASEGRANT
Stock grant
42,000——825,465Jan 24, 2024Jan 25, 2024 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
SALE
President and CEO
4,114$0.82$3.4K783,465Jan 4, 2024Jan 8, 2024 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
SALE
President and CEO
3,622$0.79$2.9K787,579Dec 4, 2023Dec 5, 2023 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
SALE
President and CEO
3,606$0.92$3.3K791,201Nov 6, 2023Nov 7, 2023 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
SALE
President and CEO
3,589$1.27$4.6K794,807Oct 4, 2023Oct 5, 2023 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
SALE
President and CEO
64$1.32$84798,396Sep 5, 2023Sep 6, 2023 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
SALE
President and CEO
3,558$1.33$4.7K798,460Sep 5, 2023Sep 6, 2023 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
SALE10b5-1
10b5-1 plan
3,722$1.72$6.4K802,018Aug 7, 2023Aug 8, 2023 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
SALE10b5-1
10b5-1 plan
3,536$2.24$7.9K809,278Jun 5, 2023Jun 7, 2023 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
SALE10b5-1
10b5-1 plan
3,805$3.35$12.8K812,814May 4, 2023May 5, 2023 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
SALE10b5-1
10b5-1 plan
3,497$3.97$13.9K816,619Apr 4, 2023Apr 5, 2023 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
SALE
President and CEO
3,506$3.16$11.1K820,116Mar 6, 2023Mar 7, 2023 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
SALE
President and CEO
33,033$3.03$100.1K823,622Mar 1, 2023Mar 2, 2023 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
PURCHASEGRANT
Stock grant
252,000——856,655Feb 28, 2023Mar 2, 2023 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
SALE
President and CEO
3,950$3.40$13.4K604,655Feb 6, 2023Feb 8, 2023 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
SALE
President and CEO
3,922$3.27$12.8K608,605Jan 4, 2023Jan 5, 2023 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
SALE
President and CEO
3,490$5.17$18.0K612,527Dec 5, 2022Dec 6, 2022 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
SALE
President and CEO
3,493$4.54$15.9K616,017Nov 4, 2022Nov 8, 2022 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
SALE
President and CEO
3,488$5.87$20.5K619,510Oct 4, 2022Oct 5, 2022 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
SALE
President and CEO
3,463$5.23$18.1K622,998Sep 8, 2022Sep 9, 2022 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
SALE
President and CEO
16$5.26$84626,461Sep 8, 2022Sep 9, 2022 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
SALE
President and CEO
2,314$4.48$10.4K626,477Aug 4, 2022Aug 5, 2022 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
SALE
President and CEO
2,115$5.18$10.9K628,791Jul 8, 2022Jul 11, 2022 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
SALE
President and CEO
2,542$5.76$14.6K630,906Jun 7, 2022Jun 8, 2022 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
SALE
President and CEO
27,869$6.23$173.5K633,448May 4, 2022May 5, 2022 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
SALE
President and CEO
633$6.26$4.0K661,317May 4, 2022May 5, 2022 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
PURCHASEGRANT
Stock grant
360,000——360,000Feb 28, 2022Mar 2, 2022 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
PURCHASEGRANT
Stock grant
288,750——661,950Feb 28, 2022Mar 2, 2022 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
PURCHASEGRANT
Stock grant
373,200——373,200May 3, 2021May 4, 2021 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
PURCHASEGRANT
Stock grant
559,800——559,800May 3, 2021May 4, 2021 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
PURCHASEGRANT
Stock grant
16,400——16,400May 21, 2020May 26, 2020 ↗View →
KPTI
KARYOPHARM THERAPEUTICS INC.
PURCHASEGRANT
Stock grant
50,000——50,000Mar 5, 2020Mar 9, 2020 ↗View →
Other insiders · KPTI
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About this filer
CIK 0001804460
ROLE
President and CEO
PRIMARY
KPTI
COMPANIES
1
ACTIVE SINCE
Mar 2020
MARKETPEEL · /INSIDER/0001804460DATA · SEC EDGAR · FORM 4 · CONSOLIDATED TAPE
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