MarketPeel
Insider Trading Intelligence
JS

Jeffrey T. L. Smith

ZYME
EVP & CHIEF MEDICAL OFFICER · ZYMEWORKS INC. · CIK 0001604800
FILING MIX · LIFETIME54%/46%
BUYS
7
SELLS
6
TOTAL VALUE
$641.4K
COMPANIES
1
ACTIVE SINCE
Jan 2024
HOLDINGS NOW
36,018
AVG SELL PX
$20.72
TRADE KIND
SHOWING 13 / 13
Trades · vs SPY
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Performance · forward returns vs SPY
3 backtested trades · 8 horizons · 6 pending
Forward-return performance of every backtestable P/S trade by Jeffrey T. L. Smith, measured at 8 horizons from 7 days to 2 years. Deduped per economic event so co-filings count once. Excess return = trade return minus SPY return over the same window.
HORIZONTRADESWIN RATEINSIDER RETURNSPY RETURNMEAN EXCESSMEDIAN EXCESST-STAT
7d3+66.67%-3.45%-1.26%-2.19%-1.11%
14d3+100.00%-3.12%-0.18%-2.94%-2.47%
30d3+66.67%-2.45%+0.27%-2.71%-0.96%
60d3+100.00%-7.91%-3.41%-4.50%-3.26%
90d3+33.33%-4.49%-6.84%+2.35%+5.60%
180d3(1 pending)+50.00%-3.28%+6.82%-10.11%-10.11%
1y3(2 pending)+0.00%+67.22%+16.55%+50.67%+50.67%
2y3(3 pending)
How to read this: Insider Returnis the average raw return of the filer's trades over the horizon. SPY Return is what SPY did over those same windows — reference only, not a comparison. The headline alpha number is Mean Excess = Insider − SPY; green means the filer beat SPY, red means they trailed it. Win rate is the share of individual trades where the filer beat SPY. T-statvalues above 2 mean the alpha is unlikely to be chance given the sample size. "Pending" counts trades where the horizon hasn't elapsed yet; their stats are not included in the row average.
Holdings over time
ZYME · 36,018 shares · as of Jan 12, 2026
022,50045,00067,50090,00020252026SHARES HELD
Trading cadence · quarterly flow
BUY SELL
2024
2024
2024
2024
2025
2025
2025
2025
2026
FLOW · 7 buys / 6 sellsCOVERAGE · 9 quarters
Form 4 filings · all activity
COMPANYTYPESHARESPRICEVALUEHELD AFTERTRADE DATEFILEDDETAILS
ZYME
ZYMEWORKS INC.
SALE
EVP & Chief Medical Officer
9,310$22.67$211.1K26,708Jan 12, 2026Jan 12, 2026View →
ZYME
ZYMEWORKS INC.
SALE
EVP & Chief Medical Officer
17,66635,334Jan 12, 2026Jan 12, 2026View →
ZYME
ZYMEWORKS INC.
PURCHASE
EVP & Chief Medical Officer
17,66636,018Jan 12, 2026Jan 12, 2026View →
ZYME
ZYMEWORKS INC.
SALE
EVP & Chief Medical Officer
10,538$25.10$264.5K18,352Jan 5, 2026Jan 5, 2026View →
ZYME
ZYMEWORKS INC.
SALE
EVP & Chief Medical Officer
20,00020,000Jan 5, 2026Jan 5, 2026View →
ZYME
ZYMEWORKS INC.
PURCHASE
EVP & Chief Medical Officer
20,00028,890Jan 5, 2026Jan 5, 2026View →
ZYME
ZYMEWORKS INC.
PURCHASEGRANT
Stock grant
79,00079,000Jan 10, 2025Jan 10, 2025View →
ZYME
ZYMEWORKS INC.
PURCHASEGRANT
Stock grant
53,00053,000Jan 10, 2025Jan 10, 2025View →
ZYME
ZYMEWORKS INC.
SALE
EVP & Chief Medical Officer
11,110$14.92$165.8K8,890Jan 6, 2025Jan 6, 2025View →
ZYME
ZYMEWORKS INC.
SALE
EVP & Chief Medical Officer
20,00040,000Jan 6, 2025Jan 6, 2025View →
ZYME
ZYMEWORKS INC.
PURCHASE
EVP & Chief Medical Officer
20,00020,000Jan 6, 2025Jan 6, 2025View →
ZYME
ZYMEWORKS INC.
PURCHASEGRANT
Stock grant
60,00060,000Jan 5, 2024Jan 8, 2024View →
ZYME
ZYMEWORKS INC.
PURCHASEGRANT
Stock grant
90,00090,000Jan 5, 2024Jan 8, 2024View →
Other insiders · ZYME
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About this filer
CIK 0001604800
ROLE
EVP & Chief Medical Officer
PRIMARY
ZYME
COMPANIES
1
ACTIVE SINCE
Jan 2024
MARKETPEEL · /INSIDER/0001604800DATA · SEC EDGAR · FORM 4 · CONSOLIDATED TAPE
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