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Insider Trading Intelligence
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Paul B. Manning

TSHA
DIRECTOR · TAYSHA GENE THERAPIES, INC. · CIK 0001494695
FILING MIX · LIFETIME78%/22%
BUYS
76
SELLS
22
TOTAL VALUE
$144.26M
COMPANIES
5
ACTIVE SINCE
Aug 2020
HOLDINGS NOW
6,703,406
AVG SELL PX
$36.82
TRADE KIND
SHOWING 98 / 98
Trades · vs SPY
Loading price series…
Performance · forward returns vs SPY
47 backtested trades · 8 horizons · 29 pending
Forward-return performance of every backtestable P/S trade by Paul B. Manning, measured at 8 horizons from 7 days to 2 years. Deduped per economic event so co-filings count once. Excess return = trade return minus SPY return over the same window.
HORIZONTRADESWIN RATEINSIDER RETURNSPY RETURNMEAN EXCESSMEDIAN EXCESST-STAT
7d47+85.11%+15.36%+0.56%+14.80%+9.92%6.32
14d47+80.85%+14.29%+1.07%+13.22%+3.82%4.00
30d47+61.70%+5.69%+0.72%+4.97%+4.15%1.14
60d47+51.06%+6.00%+1.88%+4.12%-10.07%0.90
90d47+38.30%-0.41%+1.50%-3.24%-6.70%-0.71
180d47(1 pending)+36.96%-0.76%+2.65%-4.94%-15.67%-0.66
1y47(9 pending)+42.11%-11.22%+9.64%-24.30%-52.36%-2.53
2y47(19 pending)+28.57%-4.77%+21.29%-26.06%-83.21%—
How to read this: Insider Returnis the average raw return of the filer's trades over the horizon. SPY Return is what SPY did over those same windows — reference only, not a comparison. The headline alpha number is Mean Excess = Insider − SPY; green means the filer beat SPY, red means they trailed it. Win rate is the share of individual trades where the filer beat SPY. T-statvalues above 2 mean the alpha is unlikely to be chance given the sample size. "Pending" counts trades where the horizon hasn't elapsed yet; their stats are not included in the row average.
Holdings over time
TSHA · 2,841,704 shares · as of May 30, 2025
04,141,6678,283,33412,425,00016,566,66720212022202320242025SHARES HELD
Trading cadence · quarterly flow
BUY ● SELL ●
2020
2020
2021
2021
2021
2021
2022
2022
2022
2022
2023
2023
2023
2023
2024
2024
2024
2024
2025
2025
2025
2025
2026
2026
FLOW · 76 buys / 22 sellsCOVERAGE · 24 quarters
Form 4 filings · all activity
COMPANYTYPESHARESPRICEVALUEHELD AFTERTRADE DATEFILEDDETAILS
CADL
CANDEL THERAPEUTICS, INC.
PURCHASEGRANT
Stock grant
2,199$8.64$19.0K2,199Jun 30, 2026Jul 1, 2026 ↗View →
CADL
CANDEL THERAPEUTICS, INC.
PURCHASEGRANT
Stock grant
32,000——32,000Jun 23, 2026Jun 24, 2026 ↗View →
LQDA
LIQUIDIA CORP
PURCHASEGRANT
Stock grant
5,882——475,465Jun 16, 2026Jun 18, 2026 ↗View →
LQDA
LIQUIDIA CORP
SALE
19,125$62.62$1.20M879,210Jun 4, 2026Jun 8, 2026 ↗View →
LQDA
LIQUIDIA CORP
SALE
11,513$63.13$726.8K804,798Jun 4, 2026Jun 8, 2026 ↗View →
LQDA
LIQUIDIA CORP
SALE
68,265$63.83$4.36M810,945Jun 4, 2026Jun 8, 2026 ↗View →
LQDA
LIQUIDIA CORP
SALE
88,487$64.28$5.69M716,311Jun 4, 2026Jun 8, 2026 ↗View →
LQDA
LIQUIDIA CORP
SALE
12,610$64.42$812.3K798,335Jun 4, 2026Jun 8, 2026 ↗View →
CADL
CANDEL THERAPEUTICS, INC.
PURCHASEGRANT
Stock grant
4,618$4.11$19.0K4,618Mar 31, 2026Apr 2, 2026 ↗View →
CADL
CANDEL THERAPEUTICS, INC.
PURCHASE
550,458$5.45$3.00M2,763,527Feb 23, 2026Feb 26, 2026 ↗View →
LQDA
LIQUIDIA CORP
SALE
55,116$42.63$2.35M0Feb 11, 2026Feb 12, 2026 ↗View →
LQDA
LIQUIDIA CORP
PURCHASE
55,116$42.63$2.35M469,583Feb 11, 2026Feb 12, 2026 ↗View →
VRCA
VERRICA PHARMACEUTICALS INC.
PURCHASE
2,750,762$4.24$11.67M3,348,372Nov 25, 2025Nov 25, 2025 ↗View →
VRCA
VERRICA PHARMACEUTICALS INC.
PURCHASE
1,375,380$4.24$5.84M3,958,189Nov 25, 2025Nov 25, 2025 ↗View →
VRCA
VERRICA PHARMACEUTICALS INC.
PURCHASE
687,690——687,690Nov 25, 2025Nov 25, 2025 ↗View →
VRCA
VERRICA PHARMACEUTICALS INC.
PURCHASE
343,845——343,845Nov 25, 2025Nov 25, 2025 ↗View →
LQDA
LIQUIDIA CORP
SALE
254,038$28.67$7.28M505,058Sep 2, 2025Sep 2, 2025 ↗View →
LQDA
LIQUIDIA CORP
SALE
74,230$29.14$2.16M430,828Sep 2, 2025Sep 2, 2025 ↗View →
LQDA
LIQUIDIA CORP
SALE
188,232$27.62$5.20M759,096Aug 29, 2025Sep 2, 2025 ↗View →
LQDA
LIQUIDIA CORP
SALE
154,337$27.94$4.31M947,328Aug 28, 2025Sep 2, 2025 ↗View →
CADL
CANDEL THERAPEUTICS, INC.
PURCHASEGRANT
Stock grant
1,070,663$4.67$5.00M2,213,069Jun 25, 2025Jun 26, 2025 ↗View →
CADL
CANDEL THERAPEUTICS, INC.
PURCHASEGRANT
Stock grant
14,240——14,240Jun 17, 2025Jun 18, 2025 ↗View →
LQDA
LIQUIDIA CORP
PURCHASEGRANT
Stock grant
18,396——38,755Jun 17, 2025Jun 20, 2025 ↗View →
TSHA
TAYSHA GENE THERAPIES, INC.
PURCHASE
750,000$2.75$2.06M2,841,704May 30, 2025Jun 3, 2025 ↗View →
CADL
CANDEL THERAPEUTICS, INC.
PURCHASE
500,000$6.00$3.00M1,142,406Dec 16, 2024Dec 18, 2024 ↗View →
CADL
CANDEL THERAPEUTICS, INC.
PURCHASE
750,000$6.00$4.50M1,303,752Dec 16, 2024Dec 18, 2024 ↗View →
VRCA
VERRICA PHARMACEUTICALS INC.
SALEGRANT
Gift
450,000——25,828,094Nov 26, 2024Nov 26, 2024 ↗View →
VRCA
VERRICA PHARMACEUTICALS INC.
PURCHASE
9,213,483——9,213,483Nov 22, 2024Nov 26, 2024 ↗View →
VRCA
VERRICA PHARMACEUTICALS INC.
PURCHASE
4,494,382——5,976,101Nov 22, 2024Nov 26, 2024 ↗View →
VRCA
VERRICA PHARMACEUTICALS INC.
PURCHASE
9,213,483——9,213,483Nov 22, 2024Nov 26, 2024 ↗View →
VRCA
VERRICA PHARMACEUTICALS INC.
PURCHASE
2,247,191——2,247,191Nov 22, 2024Nov 26, 2024 ↗View →
VRCA
VERRICA PHARMACEUTICALS INC.
PURCHASE
18,426,966——26,278,094Nov 22, 2024Nov 26, 2024 ↗View →
VRCA
VERRICA PHARMACEUTICALS INC.
PURCHASE
2,247,191——2,247,191Nov 22, 2024Nov 26, 2024 ↗View →
VRCA
VERRICA PHARMACEUTICALS INC.
PURCHASEGRANT
Gift
891,870.41——891,870.41Sep 19, 2024Sep 23, 2024 ↗View →
VRCA
VERRICA PHARMACEUTICALS INC.
PURCHASEGRANT
Gift
891,870.42——891,870.42Sep 19, 2024Sep 23, 2024 ↗View →
VRCA
VERRICA PHARMACEUTICALS INC.
SALEGRANT
Gift
2,675,611.25——0Sep 19, 2024Sep 23, 2024 ↗View →
LQDA
LIQUIDIA CORP
PURCHASE
337,078$8.90$3.00M816,311Sep 12, 2024Sep 16, 2024 ↗View →
TSHA
TAYSHA GENE THERAPIES, INC.
PURCHASE
1,333,333$2.25$3.00M1,333,333Jun 27, 2024Jul 1, 2024 ↗View →
CADL
CANDEL THERAPEUTICS, INC.
PURCHASEGRANT
Stock grant
14,240——14,240Jun 26, 2024Jun 27, 2024 ↗View →
LQDA
LIQUIDIA CORP
PURCHASEGRANT
Stock grant
20,359——299,689Jun 20, 2024Jun 24, 2024 ↗View →
LQDA
LIQUIDIA CORP
PURCHASE
279,330$7.16$2.00M279,330Dec 14, 2023Dec 18, 2023 ↗View →
TSHA
TAYSHA GENE THERAPIES, INC.
PURCHASE
100,000$1.63$163.0K16,566,667Nov 17, 2023Nov 20, 2023 ↗View →
TSHA
TAYSHA GENE THERAPIES, INC.
PURCHASE
16,466,667$0.90$14.82M16,466,667Aug 16, 2023Aug 16, 2023 ↗View →
VRCA
VERRICA PHARMACEUTICALS INC.
PURCHASE
200,000$5.02$1.00M7,851,128Jul 24, 2023Jul 24, 2023 ↗View →
CADL
CANDEL THERAPEUTICS, INC.
PURCHASEGRANT
Stock grant
14,240——14,240Jun 28, 2023Jun 29, 2023 ↗View →
LQDA
LIQUIDIA CORP
PURCHASEGRANT
Stock grant
20,000——20,000Jun 19, 2023Jun 21, 2023 ↗View →
TSHA
TAYSHA GENE THERAPIES, INC.
PURCHASE
1,500,000$2.00$3.00M1,642,202Oct 31, 2022Nov 2, 2022 ↗View →
CADL
CANDEL THERAPEUTICS, INC.
PURCHASEGRANT
Stock grant
14,240——14,240Oct 13, 2022Oct 17, 2022 ↗View →
VRCA
VERRICA PHARMACEUTICALS INC.
PURCHASE
4,761,904$2.10$10.00M13,651,128Jul 5, 2022Jul 5, 2022 ↗View →
LQDA
LIQUIDIA CORP
PURCHASEGRANT
Stock grant
20,000——20,000Jun 17, 2022Jun 22, 2022 ↗View →
TSHA
TAYSHA GENE THERAPIES, INC.
PURCHASEGRANT
Stock grant
15,500——15,500Jun 17, 2022Jun 22, 2022 ↗View →
LQDA
LIQUIDIA CORP
PURCHASE
392,156$5.10$2.00M392,156Apr 18, 2022Apr 19, 2022 ↗View →
LQDA
LIQUIDIA CORP
PURCHASEGRANT
Stock grant
435,674——435,674Mar 31, 2022Apr 20, 2022 ↗View →
TSHA
TAYSHA GENE THERAPIES, INC.
PURCHASE
50,000$7.84$392.0K142,202Feb 3, 2022Feb 4, 2022 ↗View →
TSHA
TAYSHA GENE THERAPIES, INC.
PURCHASE
26,602$7.84$208.6K2,091,704Feb 3, 2022Feb 4, 2022 ↗View →
TSHA
TAYSHA GENE THERAPIES, INC.
PURCHASE
22,000$7.77$170.9K22,000Feb 2, 2022Feb 4, 2022 ↗View →
TSHA
TAYSHA GENE THERAPIES, INC.
PURCHASE
45,000$7.77$349.6K2,065,102Feb 2, 2022Feb 4, 2022 ↗View →
TSHA
TAYSHA GENE THERAPIES, INC.
PURCHASE
58,000$7.77$450.7K92,202Feb 2, 2022Feb 4, 2022 ↗View →
VRCA
VERRICA PHARMACEUTICALS INC.
PURCHASE
19,977$9.22$184.2K8,149,394Dec 3, 2021Dec 6, 2021 ↗View →
VRCA
VERRICA PHARMACEUTICALS INC.
PURCHASE
30,023$9.45$283.7K8,129,417Dec 2, 2021Dec 6, 2021 ↗View →
TSHA
TAYSHA GENE THERAPIES, INC.
PURCHASE
2,202$13.19$29.0K34,202Nov 24, 2021Nov 29, 2021 ↗View →
TSHA
TAYSHA GENE THERAPIES, INC.
PURCHASE
20,000$12.54$250.8K32,000Nov 23, 2021Nov 24, 2021 ↗View →
LQDA
LIQUIDIA CORP
PURCHASEGRANT
Stock grant
20,000——20,000Aug 20, 2021Sep 1, 2021 ↗View →
CADL
CANDEL THERAPEUTICS, INC.
SALE
1,361,069——0Jul 29, 2021Aug 4, 2021 ↗View →
CADL
CANDEL THERAPEUTICS, INC.
PURCHASE
553,752——553,752Jul 29, 2021Aug 4, 2021 ↗View →
CADL
CANDEL THERAPEUTICS, INC.
SALE
1,669,303——0Jul 29, 2021Aug 4, 2021 ↗View →
CADL
CANDEL THERAPEUTICS, INC.
PURCHASE
20,000$7.30$145.9K56,000Jul 29, 2021Jul 29, 2021 ↗View →
CADL
CANDEL THERAPEUTICS, INC.
SALE
1,669,303——0Jul 29, 2021Aug 2, 2021 ↗View →
CADL
CANDEL THERAPEUTICS, INC.
PURCHASE
679,158——679,158Jul 29, 2021Aug 2, 2021 ↗View →
CADL
CANDEL THERAPEUTICS, INC.
SALE
1,361,069——0Jul 29, 2021Aug 2, 2021 ↗View →
CADL
CANDEL THERAPEUTICS, INC.
PURCHASE
553,752——553,752Jul 29, 2021Aug 2, 2021 ↗View →
CADL
CANDEL THERAPEUTICS, INC.
PURCHASE
679,158——679,158Jul 29, 2021Aug 4, 2021 ↗View →
CADL
CANDEL THERAPEUTICS, INC.
PURCHASE
1,625,000$8.00$13.00M1,681,000Jul 29, 2021Aug 4, 2021 ↗View →
CADL
CANDEL THERAPEUTICS, INC.
PURCHASE
36,000$7.36$264.8K36,000Jul 27, 2021Jul 29, 2021 ↗View →
ABOS
ACUMEN PHARMACEUTICALS, INC.
SALE
1,634,515——0Jul 6, 2021Jul 8, 2021 ↗View →
ABOS
ACUMEN PHARMACEUTICALS, INC.
SALE
657,985——0Jul 6, 2021Jul 8, 2021 ↗View →
ABOS
ACUMEN PHARMACEUTICALS, INC.
SALE
1,315,969——0Jul 6, 2021Jul 8, 2021 ↗View →
ABOS
ACUMEN PHARMACEUTICALS, INC.
PURCHASE
312,500$16.00$5.00M3,352,693Jul 6, 2021Jul 8, 2021 ↗View →
ABOS
ACUMEN PHARMACEUTICALS, INC.
PURCHASE
657,985——657,985Jul 6, 2021Jul 8, 2021 ↗View →
ABOS
ACUMEN PHARMACEUTICALS, INC.
PURCHASE
2,950,484——3,040,193Jul 6, 2021Jul 8, 2021 ↗View →
TSHA
TAYSHA GENE THERAPIES, INC.
PURCHASEGRANT
Stock grant
15,500——15,500Jun 17, 2021Jun 21, 2021 ↗View →
TSHA
TAYSHA GENE THERAPIES, INC.
PURCHASE
12,000$20.98$251.8K12,000May 14, 2021May 17, 2021 ↗View →
LQDA
LIQUIDIA CORP
PURCHASE
198,413$2.52$500.0K737,646Apr 13, 2021Apr 14, 2021 ↗View →
VRCA
VERRICA PHARMACEUTICALS INC.
PURCHASE
739,830$14.75$10.91M739,830Mar 25, 2021Mar 29, 2021 ↗View →
LQDA
LIQUIDIA CORP
PURCHASEGRANT
Stock grant
21,385——21,385Mar 24, 2021Mar 26, 2021 ↗View →
LQDA
LIQUIDIA CORP
PURCHASEGRANT
Stock grant
30,000——30,000Nov 18, 2020Nov 19, 2020 ↗View →
TSHA
TAYSHA GENE THERAPIES, INC.
PURCHASE
2,008,158——2,008,158Sep 28, 2020Sep 30, 2020 ↗View →
TSHA
TAYSHA GENE THERAPIES, INC.
SALE
10,963——0Sep 28, 2020Sep 30, 2020 ↗View →
TSHA
TAYSHA GENE THERAPIES, INC.
SALE
1,843,193——0Sep 28, 2020Sep 30, 2020 ↗View →
TSHA
TAYSHA GENE THERAPIES, INC.
SALE
3,006,155——0Sep 28, 2020Sep 30, 2020 ↗View →
TSHA
TAYSHA GENE THERAPIES, INC.
PURCHASE
11,944——2,020,102Sep 28, 2020Sep 30, 2020 ↗View →
TSHA
TAYSHA GENE THERAPIES, INC.
PURCHASE
3,275,205——3,275,205Sep 28, 2020Sep 30, 2020 ↗View →
TSHA
TAYSHA GENE THERAPIES, INC.
PURCHASEGRANT
Stock grant
31,000——31,000Sep 23, 2020Sep 25, 2020 ↗View →
VRCA
VERRICA PHARMACEUTICALS INC.
PURCHASE
20,000$9.09$181.8K8,099,394Aug 20, 2020Aug 21, 2020 ↗View →
VRCA
VERRICA PHARMACEUTICALS INC.
PURCHASE
10,000$8.55$85.5K1,481,719Aug 18, 2020Aug 19, 2020 ↗View →
VRCA
VERRICA PHARMACEUTICALS INC.
PURCHASE
6,000$6.92$41.5K1,471,719Aug 17, 2020Aug 18, 2020 ↗View →
VRCA
VERRICA PHARMACEUTICALS INC.
PURCHASE
50,000$6.51$325.5K1,465,719Aug 14, 2020Aug 17, 2020 ↗View →
VRCA
VERRICA PHARMACEUTICALS INC.
PURCHASE
108,500$6.41$695.5K1,415,719Aug 13, 2020Aug 17, 2020 ↗View →
Other insiders · TSHA
Loading peer insiders…
About this filer
CIK 0001494695
ROLE
Director
PRIMARY
TSHA
COMPANIES
5
ACTIVE SINCE
Aug 2020
MARKETPEEL · /INSIDER/0001494695DATA · SEC EDGAR · FORM 4 · CONSOLIDATED TAPE
FREE · DAILY · 6 AM ET

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One short email. Insider buys, congressional trades, and plain-English analysis.

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