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JF

James M. Frates

AMLX
CHIEF FINANCIAL OFFICER · AMYLYX PHARMACEUTICALS, INC. · CIK 0001235598
FILING MIX · LIFETIME53%/47%
BUYS
32
SELLS
28
TOTAL VALUE
$4.71M
COMPANIES
2
ACTIVE SINCE
Feb 2020
HOLDINGS NOW
353,456
AVG SELL PX
$24.56
TRADE KIND
SHOWING 60 / 60
Trades · vs SPY
Loading price series…
Performance · forward returns vs SPY
14 backtested trades · 8 horizons · 13 pending
Forward-return performance of every backtestable P/S trade by James M. Frates, measured at 8 horizons from 7 days to 2 years. Deduped per economic event so co-filings count once. Excess return = trade return minus SPY return over the same window.
HORIZONTRADESWIN RATEINSIDER RETURNSPY RETURNMEAN EXCESSMEDIAN EXCESST-STAT
7d14+78.57%-6.28%+0.02%-6.30%-1.33%—
14d14+64.29%-4.82%+0.70%-5.53%-2.91%—
30d14+57.14%-1.94%+2.84%-4.78%-8.28%—
60d14+50.00%+2.42%+3.96%-1.53%-5.52%—
90d14+64.29%-8.33%+6.76%-15.26%-27.28%—
180d14(3 pending)+72.73%-7.87%+10.56%-18.42%-58.19%—
1y14(4 pending)+70.00%+2.59%+24.64%-22.04%-100.81%—
2y14(6 pending)+75.00%-72.00%+48.46%-120.46%-133.02%—
How to read this: Insider Returnis the average raw return of the filer's trades over the horizon. SPY Return is what SPY did over those same windows — reference only, not a comparison. The headline alpha number is Mean Excess = Insider − SPY; green means the filer beat SPY, red means they trailed it. Win rate is the share of individual trades where the filer beat SPY. T-statvalues above 2 mean the alpha is unlikely to be chance given the sample size. "Pending" counts trades where the horizon hasn't elapsed yet; their stats are not included in the row average.
Holdings over time
AMLX · 261,628 shares · as of Mar 5, 2026
0111,750223,500335,250447,0002023202420252026SHARES HELD
Trading cadence · quarterly flow
BUY ● SELL ●
2020
2020
2020
2020
2021
2021
2021
2021
2022
2022
2022
2022
2023
2023
2023
2023
2024
2024
2024
2024
2025
2025
2025
2025
2026
FLOW · 32 buys / 28 sellsCOVERAGE · 25 quarters
Form 4 filings · all activity
COMPANYTYPESHARESPRICEVALUEHELD AFTERTRADE DATEFILEDDETAILS
AMLX
AMYLYX PHARMACEUTICALS, INC.
PURCHASEGRANT
Stock grant
143,985——143,985Mar 5, 2026Mar 9, 2026 ↗View →
AMLX
AMYLYX PHARMACEUTICALS, INC.
PURCHASEGRANT
Stock grant
95,990——261,628Mar 5, 2026Mar 9, 2026 ↗View →
AMLX
AMYLYX PHARMACEUTICALS, INC.
SALE
Chief Financial Officer
7,909$14.52$114.9K165,638Mar 2, 2026Mar 4, 2026 ↗View →
AMLX
AMYLYX PHARMACEUTICALS, INC.
SALE
Chief Financial Officer
3,557$14.65$52.1K173,547Feb 2, 2026Feb 4, 2026 ↗View →
AMLX
AMYLYX PHARMACEUTICALS, INC.
SALE
Chief Financial Officer
3,326$11.11$37.0K177,104Jan 6, 2026Jan 8, 2026 ↗View →
AMLX
AMYLYX PHARMACEUTICALS, INC.
SALE
Chief Financial Officer
10,558$14.65$154.7K280,430Sep 30, 2025Oct 2, 2025 ↗View →
AMLX
AMYLYX PHARMACEUTICALS, INC.
SALE
Chief Financial Officer
10,896$3.47$37.8K290,988Mar 31, 2025Apr 2, 2025 ↗View →
AMLX
AMYLYX PHARMACEUTICALS, INC.
PURCHASEGRANT
Stock grant
68,420——301,884Mar 6, 2025Mar 10, 2025 ↗View →
AMLX
AMYLYX PHARMACEUTICALS, INC.
PURCHASEGRANT
Stock grant
102,630——102,630Mar 6, 2025Mar 10, 2025 ↗View →
AMLX
AMYLYX PHARMACEUTICALS, INC.
PURCHASE
Chief Financial Officer
40,000$2.53$101.4K233,464Sep 12, 2024Sep 16, 2024 ↗View →
AMLX
AMYLYX PHARMACEUTICALS, INC.
PURCHASEGRANT
Stock grant
120,000——120,000Apr 16, 2024Apr 18, 2024 ↗View →
AMLX
AMYLYX PHARMACEUTICALS, INC.
PURCHASEGRANT
Stock grant
91,180——225,964Apr 16, 2024Apr 18, 2024 ↗View →
AMLX
AMYLYX PHARMACEUTICALS, INC.
SALE
Chief Financial Officer
1,792$18.73$33.6K134,784Mar 5, 2024Mar 7, 2024 ↗View →
AMLX
AMYLYX PHARMACEUTICALS, INC.
PURCHASEGRANT
Stock grant
40,000——152,035Feb 26, 2024Feb 28, 2024 ↗View →
AMLX
AMYLYX PHARMACEUTICALS, INC.
PURCHASEGRANT
Stock grant
60,000——60,000Feb 26, 2024Feb 28, 2024 ↗View →
AMLX
AMYLYX PHARMACEUTICALS, INC.
SALE
Chief Financial Officer
2,716$16.33$44.3K112,035Jan 9, 2024Jan 11, 2024 ↗View →
AMLX
AMYLYX PHARMACEUTICALS, INC.
PURCHASEGRANT
Gift
11,072——11,072Oct 31, 2023Nov 2, 2023 ↗View →
AMLX
AMYLYX PHARMACEUTICALS, INC.
PURCHASE
Chief Financial Officer
18,165$6.88$125.0K73,841Aug 23, 2023Sep 5, 2024 ↗View →
AMLX
AMYLYX PHARMACEUTICALS, INC.
SALE
Chief Financial Officer
18,165——363,835Aug 23, 2023Sep 5, 2024 ↗View →
AMLX
AMYLYX PHARMACEUTICALS, INC.
PURCHASE
Chief Financial Officer
18,165$6.88$125.0K106,341Aug 23, 2023Aug 24, 2023 ↗View →
AMLX
AMYLYX PHARMACEUTICALS, INC.
SALE
Chief Financial Officer
18,165——363,835Aug 23, 2023Aug 24, 2023 ↗View →
AMLX
AMYLYX PHARMACEUTICALS, INC.
SALE
Chief Financial Officer
32,500——382,000May 16, 2023May 18, 2023 ↗View →
AMLX
AMYLYX PHARMACEUTICALS, INC.
SALE10b5-1
10b5-1 plan
500$27.60$13.8K55,676May 16, 2023May 18, 2023 ↗View →
AMLX
AMYLYX PHARMACEUTICALS, INC.
PURCHASE
Chief Financial Officer
32,500$6.88$223.6K88,176May 16, 2023May 18, 2023 ↗View →
AMLX
AMYLYX PHARMACEUTICALS, INC.
SALE10b5-1
10b5-1 plan
32,000$26.93$861.7K56,176May 16, 2023May 18, 2023 ↗View →
AMLX
AMYLYX PHARMACEUTICALS, INC.
PURCHASEGRANT
Stock grant
97,500——97,500Mar 16, 2023Mar 24, 2023 ↗View →
AMLX
AMYLYX PHARMACEUTICALS, INC.
PURCHASEGRANT
Stock grant
21,667——55,676Mar 16, 2023Mar 24, 2023 ↗View →
AMLX
AMYLYX PHARMACEUTICALS, INC.
SALE
Chief Financial Officer
30,796$31.86$981.1K35,713Mar 16, 2023Mar 24, 2023 ↗View →
AMLX
AMYLYX PHARMACEUTICALS, INC.
SALE
Chief Financial Officer
1,704$32.46$55.3K34,009Mar 16, 2023Mar 24, 2023 ↗View →
AMLX
AMYLYX PHARMACEUTICALS, INC.
SALE
Chief Financial Officer
32,500——414,500Mar 16, 2023Mar 24, 2023 ↗View →
AMLX
AMYLYX PHARMACEUTICALS, INC.
SALE
Chief Financial Officer
30,796$31.86$981.1K3,213Mar 16, 2023Mar 20, 2023 ↗View →
AMLX
AMYLYX PHARMACEUTICALS, INC.
SALE
Chief Financial Officer
1,704$32.46$55.3K1,509Mar 16, 2023Mar 20, 2023 ↗View →
AMLX
AMYLYX PHARMACEUTICALS, INC.
PURCHASEGRANT
Stock grant
21,667——23,176Mar 16, 2023Mar 20, 2023 ↗View →
AMLX
AMYLYX PHARMACEUTICALS, INC.
PURCHASEGRANT
Stock grant
97,500——97,500Mar 16, 2023Mar 20, 2023 ↗View →
AMLX
AMYLYX PHARMACEUTICALS, INC.
PURCHASE
Chief Financial Officer
32,500$6.88$223.6K66,509Mar 16, 2023Mar 24, 2023 ↗View →
AMLX
AMYLYX PHARMACEUTICALS, INC.
PURCHASE
Chief Financial Officer
822$36.79$30.2K34,009Jan 6, 2023Jan 10, 2023 ↗View →
AMLX
AMYLYX PHARMACEUTICALS, INC.
PURCHASE
Chief Financial Officer
1,836$36.08$66.2K34,831Jan 6, 2023Jan 10, 2023 ↗View →
AMLX
AMYLYX PHARMACEUTICALS, INC.
SALE
Chief Financial Officer
5,000——447,000Dec 30, 2022Jan 4, 2023 ↗View →
AMLX
AMYLYX PHARMACEUTICALS, INC.
PURCHASE
Chief Financial Officer
5,000$6.88$34.4K36,667Dec 30, 2022Jan 4, 2023 ↗View →
AMLX
AMYLYX PHARMACEUTICALS, INC.
PURCHASEGRANT
Stock grant
25,000——25,000Feb 11, 2022Mar 28, 2022 ↗View →
AMLX
AMYLYX PHARMACEUTICALS, INC.
SALE
Chief Financial Officer
19,482——0Jan 6, 2022Apr 26, 2023 ↗View →
AMLX
AMYLYX PHARMACEUTICALS, INC.
PURCHASE
Chief Financial Officer
19,482——19,482Jan 6, 2022Apr 26, 2023 ↗View →
AMLX
AMYLYX PHARMACEUTICALS, INC.
PURCHASEGRANT
Stock grant
31,667——31,667Jan 6, 2022Jan 10, 2022 ↗View →
AMLX
AMYLYX PHARMACEUTICALS, INC.
PURCHASEGRANT
Stock grant
142,500——142,500Jan 6, 2022Jan 10, 2022 ↗View →
ALKS
ALKERMES PLC.
SALE
SVP, Alks Inc; CFO ALKS
21,983——0May 14, 2020May 14, 2020 ↗View →
ALKS
ALKERMES PLC.
PURCHASE
SVP, Alks Inc; CFO ALKS
21,983$11.74$258.1K91,828May 14, 2020May 14, 2020 ↗View →
ALKS
ALKERMES PLC.
SALE
SVP, Alks Inc; CFO ALKS
1,323$20.84$27.6K69,845Mar 1, 2020Mar 3, 2020 ↗View →
ALKS
ALKERMES PLC.
SALE
SVP, Alks Inc; CFO ALKS
4,500——0Mar 1, 2020Mar 3, 2020 ↗View →
ALKS
ALKERMES PLC.
PURCHASE
SVP, Alks Inc; CFO ALKS
4,500——71,168Mar 1, 2020Mar 3, 2020 ↗View →
ALKS
ALKERMES PLC.
PURCHASE
SVP, Alks Inc; CFO ALKS
5,825——68,380Feb 21, 2020Feb 24, 2020 ↗View →
ALKS
ALKERMES PLC.
SALE
SVP, Alks Inc; CFO ALKS
5,825——17,475Feb 21, 2020Feb 24, 2020 ↗View →
ALKS
ALKERMES PLC.
SALE
SVP, Alks Inc; CFO ALKS
1,712$20.24$34.7K66,668Feb 21, 2020Feb 24, 2020 ↗View →
ALKS
ALKERMES PLC.
PURCHASEGRANT
Stock grant
102,337——102,337Feb 20, 2020Feb 24, 2020 ↗View →
ALKS
ALKERMES PLC.
PURCHASEGRANT
Stock grant
24,474——24,474Feb 20, 2020Feb 24, 2020 ↗View →
ALKS
ALKERMES PLC.
PURCHASE
SVP, Alks Inc; CFO ALKS
3,000——63,459Feb 17, 2020Feb 18, 2020 ↗View →
ALKS
ALKERMES PLC.
SALE
SVP, Alks Inc; CFO ALKS
3,000——3,000Feb 17, 2020Feb 18, 2020 ↗View →
ALKS
ALKERMES PLC.
SALE
SVP, Alks Inc; CFO ALKS
904$17.77$16.1K62,555Feb 17, 2020Feb 18, 2020 ↗View →
ALKS
ALKERMES PLC.
SALE
SVP, Alks Inc; CFO ALKS
3,375——6,750Feb 16, 2020Feb 18, 2020 ↗View →
ALKS
ALKERMES PLC.
PURCHASE
SVP, Alks Inc; CFO ALKS
3,375——61,631Feb 16, 2020Feb 18, 2020 ↗View →
ALKS
ALKERMES PLC.
SALE
SVP, Alks Inc; CFO ALKS
1,172$17.77$20.8K60,459Feb 16, 2020Feb 18, 2020 ↗View →
Other insiders · AMLX
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About this filer
CIK 0001235598
ROLE
Chief Financial Officer
PRIMARY
AMLX
COMPANIES
2
ACTIVE SINCE
Feb 2020
MARKETPEEL · /INSIDER/0001235598DATA · SEC EDGAR · FORM 4 · CONSOLIDATED TAPE
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