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Insider Trading Intelligence
Pricing
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JK

Joseph III Klein

IONS
DIRECTOR · IONIS PHARMACEUTICALS INC · CIK 0001206369
FILING MIX · LIFETIME40%/60%
BUYS
36
SELLS
53
TOTAL VALUE
$13.09M
COMPANIES
1
ACTIVE SINCE
Jul 2020
HOLDINGS NOW
11,014
AVG SELL PX
$64.01
TRADE KIND
SHOWING 89 / 89
Trades · vs SPY
Loading price series…
Performance · forward returns vs SPY
24 backtested trades · 8 horizons · 28 pendingHow are these numbers computed? →
Forward-return performance of every backtestable P/S trade by Joseph III Klein, measured at 8 horizons from 7 days to 2 years. Deduped per economic event so co-filings count once. Excess return = trade return minus SPY return over the same window.
HORIZONTRADESWIN RATEINSIDER RETURNSPY RETURNMEAN EXCESSMEDIAN EXCESST-STAT
7d24+70.83%-2.41%+1.09%-3.49%-3.36%—
14d24+66.67%-3.93%+2.30%-6.23%-4.57%—
30d24+62.50%-0.77%+2.84%-3.83%-3.68%—
60d24+25.00%+4.46%+4.64%+0.06%-0.17%—
90d24(2 pending)+31.82%+10.16%+5.34%+6.86%+15.73%—
180d24(7 pending)+82.35%-4.03%+12.03%-15.89%-20.61%—
1y24(9 pending)+66.67%-9.91%+17.33%-27.24%-34.16%—
2y24(10 pending)+14.29%+42.53%+41.03%+1.50%+1.96%—
How to read this: Insider Returnis the average raw return of the filer's trades over the horizon. SPY Return is what SPY did over those same windows — reference only, not a comparison. The headline alpha number is Mean Excess = Insider − SPY; green means the filer beat SPY, red means they trailed it. Win rate is the share of individual trades where the filer beat SPY. T-statvalues above 2 mean the alpha is unlikely to be chance given the sample size. "Pending" counts trades where the horizon hasn't elapsed yet; their stats are not included in the row average.
Holdings over time
IONS · 11,014 shares · as of Jul 1, 2026
08,33416,66825,00133,335202120222023202420252026SHARES HELD
Trading cadence · quarterly flow
BUY ● SELL ●
2020
2020
2021
2021
2021
2021
2022
2022
2022
2022
2023
2023
2023
2023
2024
2024
2024
2024
2025
2025
2025
2025
2026
2026
2026
FLOW · 36 buys / 53 sellsCOVERAGE · 25 quarters
Form 4 filings · all activity
COMPANYTYPESHARESPRICEVALUEHELD AFTERTRADE DATEFILEDDETAILS
IONS
IONIS PHARMACEUTICALS INC
SALE
11,518——0Jul 1, 2026Jul 6, 2026 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
11,518$39.94$460.0K22,532Jul 1, 2026Jul 6, 2026 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE10b5-1
10b5-1 plan
99$79.45$7.9K22,433Jul 1, 2026Jul 6, 2026 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE10b5-1
10b5-1 plan
11,419$79.04$902.6K11,014Jul 1, 2026Jul 6, 2026 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASEGRANT
Stock grant
2,301——16,277Jul 1, 2026Jul 6, 2026 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASEGRANT
Stock grant
5,369——5,369Jul 1, 2026Jul 6, 2026 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
10,111——0May 1, 2026May 4, 2026 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE10b5-1
10b5-1 plan
1,431$74.45$106.5K11,014May 1, 2026May 4, 2026 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
10,111$47.11$476.3K21,125May 1, 2026May 4, 2026 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE10b5-1
10b5-1 plan
8,680$73.35$636.7K12,445May 1, 2026May 4, 2026 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE10b5-1
10b5-1 plan
20,105$75.50$1.52M13,230Apr 1, 2026Apr 2, 2026 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE10b5-1
10b5-1 plan
2,216$75.95$168.3K11,014Apr 1, 2026Apr 2, 2026 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
10,321——0Apr 1, 2026Apr 2, 2026 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
12,000——0Apr 1, 2026Apr 2, 2026 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
12,000$38.06$456.7K23,014Apr 1, 2026Apr 2, 2026 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
10,321$41.08$424.0K33,335Apr 1, 2026Apr 2, 2026 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE10b5-1
10b5-1 plan
1,012$80.82$81.8K11,014Mar 3, 2026Mar 5, 2026 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
4,000$42.88$171.5K32,346Mar 3, 2026Mar 5, 2026 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE10b5-1
10b5-1 plan
6,794$80.00$543.5K12,026Mar 3, 2026Mar 5, 2026 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
4,000——0Mar 3, 2026Mar 5, 2026 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
12,000$40.05$480.6K28,346Mar 3, 2026Mar 5, 2026 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE10b5-1
10b5-1 plan
13,526$79.17$1.07M18,820Mar 3, 2026Mar 5, 2026 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
12,000——0Mar 3, 2026Mar 5, 2026 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
4,000——0Nov 25, 2025Nov 28, 2025 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
4,000——8,000Nov 25, 2025Nov 28, 2025 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE10b5-1
10b5-1 plan
4,000$80.00$320.0K0Nov 25, 2025Nov 28, 2025 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
4,000——4,000Nov 25, 2025Nov 28, 2025 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
4,000——4,000Nov 25, 2025Nov 28, 2025 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE10b5-1
10b5-1 plan
28,000$60.00$1.68M0Sep 3, 2025Sep 4, 2025 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
12,000——0Sep 3, 2025Sep 4, 2025 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
16,000——0Sep 3, 2025Sep 4, 2025 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
16,000——16,000Sep 3, 2025Sep 4, 2025 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
12,000——28,000Sep 3, 2025Sep 4, 2025 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
16,000——16,000Sep 3, 2025Sep 4, 2025 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
12,000——0Sep 3, 2025Sep 4, 2025 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
16,000——0Sep 3, 2025Sep 4, 2025 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE10b5-1
10b5-1 plan
28,000$60.00$1.68M0Sep 3, 2025Sep 4, 2025 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
12,000——28,000Sep 3, 2025Sep 4, 2025 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASEGRANT
Stock grant
5,220——13,976Jul 1, 2025Jul 2, 2025 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASEGRANT
Stock grant
11,518——11,518Jul 1, 2025Jul 2, 2025 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE10b5-1
10b5-1 plan
12,000$50.00$600.0K0Jul 16, 2024Jul 16, 2024 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
12,000——0Jul 16, 2024Jul 16, 2024 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
12,000$24.42$293.0K12,000Jul 16, 2024Jul 16, 2024 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASEGRANT
Stock grant
4,079——8,756Jul 1, 2024Jul 2, 2024 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASEGRANT
Stock grant
10,111——10,111Jul 1, 2024Jul 2, 2024 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE10b5-1
10b5-1 plan
682$42.94$29.3K4,000May 3, 2024May 6, 2024 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE10b5-1
10b5-1 plan
1,269$42.59$54.0K2,731May 3, 2024May 6, 2024 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE10b5-1
10b5-1 plan
1,318$42.57$56.1K4,682May 3, 2024May 6, 2024 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE10b5-1
10b5-1 plan
731$42.98$31.4K2,000May 3, 2024May 6, 2024 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE10b5-1
10b5-1 plan
1,070$42.55$45.5K930May 3, 2024May 6, 2024 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE10b5-1
10b5-1 plan
930$42.90$39.9K0May 3, 2024May 6, 2024 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE10b5-1
10b5-1 plan
2,000$50.00$100.0K16,346Nov 15, 2023Nov 17, 2023 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE10b5-1
10b5-1 plan
2,000$45.13$90.3K18,346Sep 26, 2023Sep 28, 2023 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
3,555$42.00$149.3K20,346Jul 18, 2023Jul 19, 2023 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
5,333——23,901Jul 17, 2023Jul 19, 2023 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
1,777——18,568Jul 17, 2023Jul 19, 2023 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
5,333——4,677Jul 17, 2023Jul 19, 2023 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
1,777——10,010Jul 17, 2023Jul 19, 2023 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
2,000$40.00$80.0K16,791Jan 17, 2023Jan 17, 2023 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
5,333——9,775Jul 15, 2022Jul 18, 2022 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
5,333——17,459Jul 15, 2022Jul 18, 2022 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
2,665——7,110Jul 15, 2022Jul 18, 2022 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
644$38.78$25.0K18,791Jul 15, 2022Jul 18, 2022 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
689$37.74$26.0K19,435Jul 15, 2022Jul 18, 2022 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
2,665——20,124Jul 15, 2022Jul 18, 2022 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASEGRANT
Stock grant
5,333——15,108Jul 1, 2022Jul 5, 2022 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASEGRANT
Stock grant
12,000——12,000Jul 1, 2022Jul 5, 2022 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
1,778——22,460Jul 15, 2021Jul 19, 2021 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
889——12,219Jul 15, 2021Jul 19, 2021 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
5,333——19,127Jul 15, 2021Jul 19, 2021 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
666——20,682Jul 15, 2021Jul 19, 2021 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
5,333——13,108Jul 15, 2021Jul 19, 2021 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
1,778——9,775Jul 15, 2021Jul 19, 2021 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
666——11,553Jul 15, 2021Jul 19, 2021 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
889——20,016Jul 15, 2021Jul 19, 2021 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
4,334$35.30$153.0K18,126Jul 15, 2021Jul 19, 2021 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASEGRANT
Stock grant
12,000——12,000Jul 1, 2021Jul 6, 2021 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASEGRANT
Stock grant
5,333——18,441Jul 1, 2021Jul 6, 2021 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
2,889$46.86$135.4K13,794Oct 20, 2020Oct 22, 2020 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
667——16,683Jul 6, 2020Jul 6, 2020 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
667——666Jul 6, 2020Jul 6, 2020 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
889——1,777Jul 2, 2020Jul 6, 2020 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
889——16,016Jul 2, 2020Jul 6, 2020 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
1,778——5,332Jul 1, 2020Jul 6, 2020 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
666——0Jul 1, 2020Jul 6, 2020 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASEGRANT
Stock grant
12,000——12,000Jul 1, 2020Jul 6, 2020 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
1,778——15,127Jul 1, 2020Jul 6, 2020 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASEGRANT
Stock grant
5,333——5,333Jul 1, 2020Jul 6, 2020 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
666——13,349Jul 1, 2020Jul 6, 2020 ↗View →
Other insiders · IONS
Loading peer insiders…
About this filer
CIK 0001206369
ROLE
Director
PRIMARY
IONS
COMPANIES
1
ACTIVE SINCE
Jul 2020
MARKETPEEL · /INSIDER/0001206369DATA · SEC EDGAR · FORM 4 · CONSOLIDATED TAPE
FREE · DAILY · 6 AM ET

The morning brief, before the bell.

One short email. Insider buys, congressional trades, and plain-English analysis.

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