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Insider Trading Intelligence
Pricing
…
CB

C. Frank Bennett

IONS
EVP, CHIEF SCIENTIFIC OFFICER · IONIS PHARMACEUTICALS INC · CIK 0001073387
FILING MIX · LIFETIME50%/50%
BUYS
58
SELLS
57
TOTAL VALUE
$41.22M
COMPANIES
1
ACTIVE SINCE
Jan 2020
HOLDINGS NOW
12,109
AVG SELL PX
$66.39
TRADE KIND
SHOWING 115 / 115
Trades · vs SPY
Loading price series…
Performance · forward returns vs SPY
27 backtested trades · 8 horizons · 34 pendingHow are these numbers computed? →
Forward-return performance of every backtestable P/S trade by C. Frank Bennett, measured at 8 horizons from 7 days to 2 years. Deduped per economic event so co-filings count once. Excess return = trade return minus SPY return over the same window.
HORIZONTRADESWIN RATEINSIDER RETURNSPY RETURNMEAN EXCESSMEDIAN EXCESST-STAT
7d27+48.15%+0.67%+0.75%-0.08%+1.40%—
14d27+55.56%+0.39%+0.75%-0.36%-1.27%—
30d27+55.56%+2.00%+1.05%+0.95%-0.68%—
60d27+59.26%+1.82%+2.82%-1.00%-4.28%—
90d27+70.37%+1.30%+4.39%-2.58%-12.42%—
180d27(8 pending)+63.16%+6.38%+13.15%-6.76%-12.71%—
1y27(12 pending)+73.33%-1.25%+27.01%-28.27%-56.25%—
2y27(14 pending)+46.15%+21.71%+39.33%-17.62%-18.99%—
How to read this: Insider Returnis the average raw return of the filer's trades over the horizon. SPY Return is what SPY did over those same windows — reference only, not a comparison. The headline alpha number is Mean Excess = Insider − SPY; green means the filer beat SPY, red means they trailed it. Win rate is the share of individual trades where the filer beat SPY. T-statvalues above 2 mean the alpha is unlikely to be chance given the sample size. "Pending" counts trades where the horizon hasn't elapsed yet; their stats are not included in the row average.
Holdings over time
IONS · 12,109 shares · as of Jul 7, 2026
041,41182,822124,232165,643202120222023202420252026SHARES HELD
Trading cadence · quarterly flow
BUY ● SELL ●
2020
2020
2020
2020
2021
2021
2021
2021
2022
2022
2022
2022
2023
2023
2023
2023
2024
2024
2024
2024
2025
2025
2025
2025
2026
2026
2026
FLOW · 58 buys / 57 sellsCOVERAGE · 27 quarters
Form 4 filings · all activity
COMPANYTYPESHARESPRICEVALUEHELD AFTERTRADE DATEFILEDDETAILS
IONS
IONIS PHARMACEUTICALS INC
SALE
EVP, Chief Scientific Officer
15,000——12,109Jul 7, 2026Jul 9, 2026 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE10b5-1
10b5-1 plan
5,536$83.58$462.7K75,018Jul 7, 2026Jul 9, 2026 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
EVP, Chief Scientific Officer
15,000——15,000Jul 7, 2026Jul 9, 2026 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE10b5-1
10b5-1 plan
15,000$85.46$1.28M0Jul 7, 2026Jul 9, 2026 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
EVP, Chief Scientific Officer
16,463$32.60$536.7K117,017Mar 3, 2026Mar 5, 2026 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
EVP, Chief Scientific Officer
48,626$60.89$2.96M165,643Mar 3, 2026Mar 5, 2026 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
EVP, Chief Scientific Officer
48,626——0Mar 3, 2026Mar 5, 2026 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE10b5-1
10b5-1 plan
12,687$79.88$1.01M81,356Mar 3, 2026Mar 5, 2026 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE10b5-1
10b5-1 plan
802$80.76$64.8K80,554Mar 3, 2026Mar 5, 2026 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE10b5-1
10b5-1 plan
71,600$79.10$5.66M94,043Mar 3, 2026Mar 5, 2026 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
EVP, Chief Scientific Officer
16,463——2,406Mar 3, 2026Mar 5, 2026 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
EVP, Chief Scientific Officer
261$48.87$12.8K100,554Feb 27, 2026Mar 3, 2026 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
EVP, Chief Scientific Officer
16,463$32.60$536.7K96,756Feb 2, 2026Feb 4, 2026 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
EVP, Chief Scientific Officer
48,626——0Feb 2, 2026Feb 4, 2026 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE10b5-1
10b5-1 plan
20,000$82.60$1.65M80,293Feb 2, 2026Feb 4, 2026 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE10b5-1
10b5-1 plan
48,626$83.03$4.04M80,293Feb 2, 2026Feb 4, 2026 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
EVP, Chief Scientific Officer
48,626$60.89$2.96M128,919Feb 2, 2026Feb 4, 2026 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
EVP, Chief Scientific Officer
16,463——2,406Feb 2, 2026Feb 4, 2026 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE10b5-1
10b5-1 plan
16,463$83.03$1.37M80,293Feb 2, 2026Feb 4, 2026 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
EVP, Chief Scientific Officer
0——100,293Feb 2, 2026Feb 13, 2026 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
EVP, Chief Scientific Officer
5,885$82.95$488.1K100,293Jan 30, 2026Feb 2, 2026 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASEGRANT
Stock grant
11,421——106,178Jan 29, 2026Feb 2, 2026 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
EVP, Chief Scientific Officer
8,977$75.15$674.6K94,757Jan 16, 2026Jan 20, 2026 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
EVP, Chief Scientific Officer
21,055——103,734Jan 15, 2026Jan 20, 2026 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
EVP, Chief Scientific Officer
21,055——17,434Jan 15, 2026Jan 20, 2026 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASEGRANT
Stock grant
25,800——89,282Jan 15, 2026Jan 20, 2026 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASEGRANT
Stock grant
9,675——27,109Jan 15, 2026Jan 20, 2026 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASEGRANT
Stock grant
19,350——19,350Jan 2, 2026Jan 5, 2026 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE10b5-1
10b5-1 plan
6,000$59.60$357.6K82,679Sep 5, 2025Sep 9, 2025 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
EVP, Chief Scientific Officer
12,891$61.50$792.8K88,679Sep 3, 2025Sep 4, 2025 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
EVP, Chief Scientific Officer
46,800——0Sep 3, 2025Sep 4, 2025 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
EVP, Chief Scientific Officer
46,800$53.77$2.52M135,479Sep 3, 2025Sep 4, 2025 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE10b5-1
10b5-1 plan
33,909$60.62$2.06M101,570Sep 3, 2025Sep 4, 2025 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE10b5-1
10b5-1 plan
5,000$49.14$245.7K88,679Sep 2, 2025Sep 4, 2025 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
EVP, Chief Scientific Officer
213$27.71$5.9K93,679Aug 29, 2025Sep 3, 2025 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE10b5-1
10b5-1 plan
10,000$43.98$439.8K93,466Aug 18, 2025Aug 20, 2025 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
EVP, Chief Scientific Officer
10,000——18,869Aug 18, 2025Aug 20, 2025 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
EVP, Chief Scientific Officer
10,000$32.60$326.0K103,466Aug 18, 2025Aug 20, 2025 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
EVP, Chief Scientific Officer
320$28.21$9.0K93,466Feb 28, 2025Mar 4, 2025 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
EVP, Chief Scientific Officer
1,327$32.46$43.1K93,146Jan 31, 2025Feb 3, 2025 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASEGRANT
Stock grant
3,607——94,473Jan 30, 2025Feb 3, 2025 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
EVP, Chief Scientific Officer
6,752$32.90$222.1K90,866Jan 16, 2025Jan 17, 2025 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASEGRANT
Stock grant
22,000——63,482Jan 15, 2025Jan 17, 2025 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASEGRANT
Stock grant
33,000——56,500Jan 15, 2025Jan 17, 2025 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
EVP, Chief Scientific Officer
18,011——38,489Jan 15, 2025Jan 17, 2025 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
EVP, Chief Scientific Officer
18,011——97,618Jan 15, 2025Jan 17, 2025 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASEGRANT
Stock grant
22,000——22,000Jan 2, 2025Jan 3, 2025 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
EVP, Chief Scientific Officer
177$38.64$6.8K79,607Aug 30, 2024Sep 4, 2024 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
Officer Level 14
383$34.43$13.2K79,462Feb 29, 2024Mar 4, 2024 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
EVP, Chief Scientific Officer
1,885$49.52$93.3K79,047Feb 2, 2024Sep 4, 2024 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
EVP, Chief Scientific Officer
1,853$49.52$91.8K79,079Feb 2, 2024Feb 2, 2024 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASEGRANT
Stock grant
3,609——80,932Feb 1, 2024Feb 2, 2024 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
EVP, Chief Scientific Officer
6,745$50.42$340.1K77,323Jan 17, 2024Jan 18, 2024 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
EVP, Chief Scientific Officer
18,314——23,500Jan 16, 2024Jan 18, 2024 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
EVP, Chief Scientific Officer
18,314——84,068Jan 16, 2024Jan 18, 2024 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASEGRANT
Stock grant
17,000——41,482Jan 15, 2024Jan 17, 2024 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASEGRANT
Stock grant
20,400——41,814Jan 15, 2024Jan 17, 2024 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASEGRANT
Stock grant
27,200——27,200Jan 2, 2024Jan 4, 2024 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
EVP, Chief Scientific Officer
16,113——0Dec 21, 2023Dec 22, 2023 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE10b5-1
10b5-1 plan
16,113$49.29$794.2K65,754Dec 21, 2023Dec 22, 2023 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
EVP, Chief Scientific Officer
16,113$47.34$762.8K81,867Dec 21, 2023Dec 22, 2023 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
EVP, Chief Scientific Officer
6,500$47.34$307.7K72,254Dec 20, 2023Dec 22, 2023 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE10b5-1
10b5-1 plan
6,500$49.64$322.6K65,754Dec 20, 2023Dec 22, 2023 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
EVP, Chief Scientific Officer
6,500——16,113Dec 20, 2023Dec 22, 2023 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE10b5-1
10b5-1 plan
8,610$50.19$432.1K65,754Dec 14, 2023Dec 15, 2023 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
EVP, Chief Scientific Officer
14,002——31,223Dec 14, 2023Dec 15, 2023 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
EVP, Chief Scientific Officer
8,610$47.34$407.6K74,364Dec 14, 2023Dec 15, 2023 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
EVP, Chief Scientific Officer
14,002$47.34$662.9K79,756Dec 14, 2023Dec 15, 2023 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE10b5-1
10b5-1 plan
14,002$49.21$689.1K65,754Dec 14, 2023Dec 15, 2023 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
EVP, Chief Scientific Officer
8,610——22,613Dec 14, 2023Dec 15, 2023 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE10b5-1
10b5-1 plan
4,460$46.50$207.4K65,754Sep 28, 2023Sep 29, 2023 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
Officer Level 14
180$30.56$5.5K70,214Aug 31, 2023Sep 1, 2023 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
EVP, Chief Scientific Officer
383$30.52$11.7K70,034Feb 28, 2023Mar 1, 2023 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
EVP, Chief Scientific Officer
1,813$40.57$73.6K69,651Feb 6, 2023Feb 7, 2023 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASEGRANT
Stock grant
3,609——71,464Feb 3, 2023Feb 7, 2023 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
EVP, Chief Scientific Officer
6,978$38.89$271.4K67,855Jan 18, 2023Jan 19, 2023 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
EVP, Chief Scientific Officer
19,417——74,833Jan 17, 2023Jan 19, 2023 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
EVP, Chief Scientific Officer
19,417——21,414Jan 17, 2023Jan 19, 2023 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASEGRANT
Stock grant
13,656——24,482Jan 15, 2023Jan 18, 2023 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASEGRANT
Stock grant
16,387——40,831Jan 15, 2023Jan 18, 2023 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASEGRANT
Stock grant
21,849——21,849Jan 3, 2023Jan 4, 2023 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
EVP, Chief Scientific Officer
183$28.97$5.3K55,416Aug 31, 2022Sep 1, 2022 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
EVP, Chief Scientific Officer
346$28.37$9.8K55,233Feb 28, 2022Mar 2, 2022 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
EVP, Chief Scientific Officer
18,842——24,444Jan 18, 2022Jan 20, 2022 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
EVP, Chief Scientific Officer
18,842——61,613Jan 18, 2022Jan 20, 2022 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
EVP, Chief Scientific Officer
6,726$30.12$202.6K54,887Jan 18, 2022Jan 20, 2022 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASEGRANT
Stock grant
14,435——43,286Jan 15, 2022Jan 19, 2022 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASEGRANT
Stock grant
10,826——10,826Jan 15, 2022Jan 19, 2022 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASEGRANT
Stock grant
28,869——28,869Jan 3, 2022Jan 5, 2022 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
EVP & Chief Scientific Officer
151$33.80$5.1K42,771Aug 31, 2021Sep 2, 2021 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
Chief Scientific Officer
112$44.54$5.0K42,620Feb 26, 2021Mar 2, 2021 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
Chief Scientific Officer
15,520——29,641Jan 15, 2021Jan 20, 2021 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
Chief Scientific Officer
15,520——47,996Jan 15, 2021Jan 20, 2021 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASEGRANT
Stock grant
20,822——20,822Jan 15, 2021Jan 20, 2021 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
Chief Scientific Officer
5,488$61.28$336.3K42,508Jan 15, 2021Jan 20, 2021 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASEGRANT
Stock grant
46,850——46,850Jan 4, 2021Jan 6, 2021 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
Chief Scientific Officer
7,947$51.04$405.6K32,476Dec 4, 2020Dec 8, 2020 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
Chief Scientific Officer
7,947——0Dec 4, 2020Dec 8, 2020 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
Chief Scientific Officer
7,947$39.87$316.8K40,423Dec 4, 2020Dec 8, 2020 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
Chief Scientific Officer
7,053——7,947Dec 2, 2020Dec 4, 2020 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
Chief Scientific Officer
7,053$39.87$281.2K39,529Dec 2, 2020Dec 4, 2020 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
Chief Scientific Officer
7,053$51.32$362.0K32,476Dec 2, 2020Dec 4, 2020 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
Chief Scientific Officer
15,000$39.87$598.0K47,476Nov 3, 2020Nov 5, 2020 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
Chief Scientific Officer
15,000$46.77$701.6K32,476Nov 3, 2020Nov 5, 2020 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
Chief Scientific Officer
15,000——15,000Nov 3, 2020Nov 5, 2020 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
Chief Scientific Officer
112$44.46$5.0K32,476Aug 31, 2020Sep 2, 2020 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
EVP, Chief Scientific Officer
15,000——30,000Jun 25, 2020Jun 29, 2020 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
EVP, Chief Scientific Officer
15,000$39.87$598.0K47,364Jun 25, 2020Jun 29, 2020 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
EVP, Chief Scientific Officer
15,000$59.77$896.5K32,364Jun 25, 2020Jun 29, 2020 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
Chief Scientific Officer
169$43.16$7.3K32,364Feb 29, 2020Mar 3, 2020 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASEGRANT
Stock grant
21,612——21,612Jan 15, 2020Jan 17, 2020 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
Chief Scientific Officer
4,162$62.06$258.3K32,195Jan 15, 2020Jan 17, 2020 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASE
Chief Scientific Officer
11,711——36,357Jan 15, 2020Jan 17, 2020 ↗View →
IONS
IONIS PHARMACEUTICALS INC
SALE
Chief Scientific Officer
11,711——23,549Jan 15, 2020Jan 17, 2020 ↗View →
IONS
IONIS PHARMACEUTICALS INC
PURCHASEGRANT
Stock grant
48,626——48,626Jan 2, 2020Jan 3, 2020 ↗View →
Other insiders · IONS
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About this filer
CIK 0001073387
ROLE
EVP, Chief Scientific Officer
PRIMARY
IONS
COMPANIES
1
ACTIVE SINCE
Jan 2020
MARKETPEEL · /INSIDER/0001073387DATA · SEC EDGAR · FORM 4 · CONSOLIDATED TAPE
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